This volume provides a brief but important summary of the essential tests that need to be performed on all new compounds--whether they are new drugs, pesticides or food additives--before they can be registered for use in the United Kingdom. These basic tests for mutagenicity, originally drawn up by the United Kingdom Environmental Mutagen Society in 1983 have now been fully revised under the auspices of expert working groups from academia and industry and in collaboration with the UK Department of Health. This volume therefore provides the latest official guidelines and recommendations for...
This volume provides a brief but important summary of the essential tests that need to be performed on all new compounds--whether they are new drugs, ...
The expertise of toxicologists and statisticians to provide a rigorous and practical account of the interpretation of mutagenicity test data has been drawn upon for this volume. Now, chemicals such as drugs, food additives and pesticides all need careful screening to eliminate potentially mutagenic compounds. Although guidelines exist on the performance of these tests, advice on data evolution is scarce. This niche is now filled by providing the statistical background necessary for toxicologists to understand, design and interpret mutagenicity tests. In addition to the nine chapters dealing...
The expertise of toxicologists and statisticians to provide a rigorous and practical account of the interpretation of mutagenicity test data has been ...
This volume provides a brief but important summary of the essential tests that need to be performed on all new compounds--whether they are new drugs, pesticides or food additives--before they can be registered for use in the United Kingdom. These basic tests for mutagenicity, originally drawn up by the United Kingdom Environmental Mutagen Society in 1983 have now been fully revised under the auspices of expert working groups from academia and industry and in collaboration with the UK Department of Health. This volume therefore provides the latest official guidelines and recommendations for...
This volume provides a brief but important summary of the essential tests that need to be performed on all new compounds--whether they are new drugs, ...
Originally published in 1993, this volume describes supplementary tests used to assess risks of in vitro mutagenicity when basic safety tests were inconclusive.
Originally published in 1993, this volume describes supplementary tests used to assess risks of in vitro mutagenicity when basic safety tests were inc...