This book introduces into a newly developing branch of biology, the semiotics of cellular communication. The number of known cell subpopulations of lymphocytes, their mediators and receptors has increased tremendously in recent years. An intercellular web of recognition and, in turn, activation or depression of various cellular functions joins all lymphocytes. This interaction of a particular lymphocyte in one subpopulation with the appropriate partner from another subpopulation for regulatory or cooperative purposes requires an efficient and unambiguous system of intercellular recognition...

This volume is the collection of papers presented during a four day meeting, the EMBO workshop "Protein Conformation as an Immunological Signal" that took place at Portovenere (La Spezia), Italy, October 1-4, 1981. The motivation that drove us to organize this meeting was the feeling that distinct groups of researchers, active in key areas of modern immunology, sometimes fail to communicate with each other simply because of different traditional affiliations. Yet it is urgent that "molecular" and "cellular" people cooperate more if immunology is to continue the exportation of new concepts to...