An indictment of the decision to close fire companies in New York City in the 1970s, and a frightening study of the way misguided and malevolent social policy can spark a chain reaction of enormous and unforeseen urban collapse.
An indictment of the decision to close fire companies in New York City in the 1970s, and a frightening study of the way misguided and malevolent socia...
Farming Human Pathogens: Ecological Resilience and Evolutionary Process
introduces a cutting-edge mathematical formalism based on the asymptotic limit theorems of information theory to describe how punctuated shifts in mesoscale ecosystems can entrain patterns of gene expression and organismal evolution. The authors apply the new formalism toward characterizing a number of infectious diseases that have evolved in response to the world as humans have made it. Many of the human pathogens that are emerging out from underneath epidemiological control are 'farmed' in the metaphorical...
Farming Human Pathogens: Ecological Resilience and Evolutionary Process
introduces a cutting-edge mathematical formalism based on the asy...
Protein folding dysfunctions like Alzheimer's and Parkinson's Diseases present intractable medical challenges: drug treatments are, at best, palliative, failing to alter ultimate disease course. Effective intervention will require a deeper understanding of protein folding and its regulation, particularly in view of a sixfold rise in the inflation-adjusted cost of bringing drugs to market since 1950. As a consequence, the pharmaceutical industry has sharply curtailed research on a range of poorly-understood afflictions, including Alzheimer's Disease. That is, in all likelihood, there will not...
Protein folding dysfunctions like Alzheimer's and Parkinson's Diseases present intractable medical challenges: drug treatments are, at best, palliativ...
Gene Expression and its Discontents examines a class of probability models describing how epigenetic context affects gene expression and organismal development, using the asymptotic limit theorems of information theory in a highly formal manner. Taking classic results on spontaneous symmetry breaking abducted from statistical physics in groupoid, rather than group, circumstances, the work suggests that epigenetic information sources act as analogs to a tunable catalyst, directing development into different characteristic pathways according to the structure of external signals. The...
Gene Expression and its Discontents examines a class of probability models describing how epigenetic context affects gene expression and o...
Gene Expression and its Discontents examines a class of probability models describing how epigenetic context affects gene expression and organismal development, using the asymptotic limit theorems of information theory in a highly formal manner. Taking classic results on spontaneous symmetry breaking abducted from statistical physics in groupoid, rather than group, circumstances, the work suggests that epigenetic information sources act as analogs to a tunable catalyst, directing development into different characteristic pathways according to the structure of external signals. The...
Gene Expression and its Discontents examines a class of probability models describing how epigenetic context affects gene expression and o...
RTW states on average also have lower life expectancy, a prevalence of obesity, and higher rates of all-cause mortality, early mortality from chronic conditions, child mortality, and risk-taking than non-RTW states.
RTW states on average also have lower life expectancy, a prevalence of obesity, and higher rates of all-cause mortality, early mortality from chronic ...