Amyotrophic Lateral Sclerosis, otherwise known as Lou Gehrig's Disease, is one of several degenerative diseases of the aging nervous system. This text neatly synthesizes the recent explosion of research into this particular condition to construct a detailed and comprehensive overview. Drs. Eisen and Krieger bring their research expertise and extensive clinical experience to provide this practical and thought-provoking account. Chapters cover the epidemiology, molecular biology, and pathophysiology of ALS, as well as issues pertinent to clinical assessment and care.