Completely revised text that reflects to emergent trends and cutting-edge advances in pharmaceutical biotechnology, this Third Edition provides a well-balanced framework for understanding every major aspect of pharmaceutical biotechnology, including drug development, production, dosage forms, administration, and therapeutic developments. New chapters cover evolving areas regarding biopharmaceuticals, including oligonucleotides, siRNA and various monoclonal antibodies, immunogenicity, gene therapy, and the regulatory issues factoring into the biopharmaceutical approval process

Updated and expanded in this Fourth Edition with information on oligonucleotides, siRNA, gene therapy and nanotech, this book covers the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use.