From pharmoeconomics and pharmacokinetics to prophylaxcis and management of infectious and autoimmune diseases, this work surveys literature on the employment of intravenous immunoglobulin (IVIG) preparations in clinical practice. It details applications of IVIG in conditions, including bone marrow and solid organ transplantation, AIDS, B-cell lymphoproliferative diseases, viral infections, rheumatoid arthritis, diabetes and Guillain-Barre syndrome.