This book is a completely revised new edition of the definitive reference on disorders of hemoglobin. Authored by world-renowned experts, the book focuses on basic science aspects and clinical features of hemoglobinopathies, covering diagnosis, treatment, and future applications of current research. While the second edition continues to address the important molecular, cellular, and genetic components, coverage of clinical issues has been significantly expanded, and there is more practical emphasis on diagnosis and management throughout. The book opens with a review of the scientific...

Science and the Quiet Art describes the experiments and the experimenters, shows how the tools of science have been applied to the study of disease through history to the present, and looks to the future. David Weatherall emphasizes the complex interplay in disease between nature, nurture, and aging and hence why, even with todays sophisticated methods, progress will be slow.Publishers Weekly describes the book as "a revealing and sobering appraisal of the successes, limitations, and promise of modern medicine."