Best friends since childhood, Gretchen, Dixie, Mary Sue, and Pamela gather on the eve of Mary Sue's 45th birthday at the lakeside cabin where "The Girlfriends Club" once convened. But at this reunion, they share the secrets of their hearts and help each other discover what they truly want out of life and how to get it.

This multi-generational story is set in small-town Texas spanning the years from World War II to the present. Two sisters, Martha Claire and Justine, move from girlhood to adulthood with different points of view and vastly different dreams. Martha Claire, the central character, is content with her small-town life. She marries Grayson Stewart, son of the town's most successful businessman, just before he is shipped overseas for duty. He is everything she ever wanted in a husband. But even more than a husband, Martha Claire wants a child. Justine has a very different plan for herself and joins...