Genomics and bioinformatics play an increasingly important and transformative role in medicine, society and agriculture. The mapping of the human genome has revealed 35,000 or so genes which might code for more than one protein, resulting in 100,000 proteins for the humans alone. Since proteins are attractive targets for developing drugs, efforts are now underway to map sequences and assign functions to many novel proteins. This book takes the novel approach to cover both the sequence and structure analysis of proteins in one volume and from an algorithmic perspective.

Key features of the...

In this book structural principals of proteins are reviewed and analysed from a geometric perspective with the aim of revealing the underlying regularities in their construction. - Willie Taylor - a recognised leader in mathematical biology/theoretical molecular biology - Protein folding determines function of protein - key research area in molecular biology and biochemistry. Computational power now means problems governing folding can be handled quantitatively. - Reviews principles of protein folding and computational techniques employed - A key area of biophysics - interfaces with many...