Stresses which arise in bioreactors can influence process performance considerably. Recent molecular biological investigations indicate that stress caused by fluid dynamical effects and extreme values of process variables and toxic substances cause similar responses in the cells. These molecular fundamentals, as well as quantitative evaluation of fluid dynamical stresses and, their effects on microorganisms, animal and plant cells and proteins are treated in this volume.
Stresses which arise in bioreactors can influence process performance considerably. Recent molecular biological investigations indicate that stress ca...
Solvent Extraction in Biotechnology deals with the reco- very and purification of primary and secondary metabolites by solvent extraction. In the first part the reaction engineering principles: definitions, thermodynamic fundamentals, and system models, the kinetics of mass transfer between two phases without and with chemical reaction as well as extraction equipment, which are important for downstream processing in biotechnology, are considered in detail. The special part of the book describes the recovery of low-molecular metabolites: alcohols, acids and antibiotics with organic...
Solvent Extraction in Biotechnology deals with the reco- very and purification of primary and secondary metabolites by solvent extraction. In t...
The book is intended to present various examples for reactor and process modeling and control as well as for metabolic flux analysis and metabolic design at an ad vanced level. In Part A, General principles and techniques with regard to reactor and process models, process control, and metabolic flux analysis are presented. In addition the accuracy, precision, and reliability of the measured data are discussed which are ex tremely important for process modeling and control. A virtual bioreactor system is presented as well, which can be used for the training of students and operators of...
The book is intended to present various examples for reactor and process modeling and control as well as for metabolic flux analysis and metabolic des...
The state of the art of the bioengineering aspects of the morphology of microorganisms and their relationship to process performance are described in this volume. Materials and methods of the digital image analysis and mathematical modeling of hyphal elongation, branching and pellet formation as well as their application to various fungi and actinomycetes during the production of antibiotics and enzymes are presented.
The state of the art of the bioengineering aspects of the morphology of microorganisms and their relationship to process performance are described in ...
