Katherine A. Fitzgerald Luke A. J. O'Neill Andy J. H. Gearing
Completely revised and expanded, this second edition of The Cytokine FactsBook is the most up-to-date reference manual available for all current well-characterized interleukins, cytokines, and their receptors. An additional 52 cytokines are included, doubling the number of entries from the previous edition. The key properties of each cytokine are described and presented in a very accessible format with diagrams for each of the receptors. The Cytokine FactsBook includes free online access to the regularly updated Cytokine Webfacts. Cytokine Webfacts is a...
Completely revised and expanded, this second edition of The Cytokine FactsBook is the most up-to-date reference manual available for all curren...
Erwin Schrodinger's book What is Life?, which was originally delivered as a set of lectures at Trinity College, Dublin, is perhaps one of the most important scientific books of the twentieth century. It marked the beginning of molecular biology, and stimulated scientists such as Watson and Crick to explore and discover the structure of DNA. The novelty and appeal of What is Life? is that Schrodinger addressed the central problems of biology--heredity and how organisms use energy to maintain order--from a physicist's perspective. Fifty years later, at Trinity College, a number of outstanding...
Erwin Schrodinger's book What is Life?, which was originally delivered as a set of lectures at Trinity College, Dublin, is perhaps one of the most imp...
The Crossroad Publishing Company once againmakes available thisexamination of the quality and quantity of the "spiritual understanding" of Scripture that developed during the Christian centuries. Far from believing that modern exegetical insights and abilities make earlier interpretations of Scripture naive curiosity, de Lubac communicates to the modern reader his own appreciation and knowledge of the irreplaceably creative role that exegesis of the church fathers and of medieval theologians played in the survival and formulating of Christianity. Even more fundamentally, he links the process...
The Crossroad Publishing Company once againmakes available thisexamination of the quality and quantity of the "spiritual understanding" of Scripture t...
Interleukins are a family of proteins that regulate the maturation, diff- entiation, or activation of cells involved in immunity and inflammation, and belong to a broader family termed cytokines. Collectively these proteins are the key orchestrators of host defense and the response to tissue injury. There are currently 23 different interleukins (numbered from IL-1 to IL-23), although the full extent of the interleukin family will only become clear upon analysis of the human genome sequence. Most important, interleukins are central to the pathogenesis of a wide range of diseases that involve...
Interleukins are a family of proteins that regulate the maturation, diff- entiation, or activation of cells involved in immunity and inflammation, and...
A repertoire of 10 TLRs mediate the first response to all microbes that infect mammals. They are the long sought receptors for a wide range of microbial products. Notable examples include TLR4 which recognizes LPS from gram negative bacteria, TLR3 which recognizes viral double-stranded RNA and TLR9 which recognizes CpG DNA motifs, found commonly in both viruses and bacteria. TLRs are increasingly being implicated in both infectious and inflammatory diseases, notable examples being sepsis, inflammatory bowel disease, atherosclerosis and asthma. There is therefore great interest in targeting...
A repertoire of 10 TLRs mediate the first response to all microbes that infect mammals. They are the long sought receptors for a wide range of micr...
Interleukins are a family of proteins that regulate the maturation, diff- entiation, or activation of cells involved in immunity and inflammation, and belong to a broader family termed cytokines. Collectively these proteins are the key orchestrators of host defense and the response to tissue injury. There are currently 23 different interleukins (numbered from IL-1 to IL-23), although the full extent of the interleukin family will only become clear upon analysis of the human genome sequence. Most important, interleukins are central to the pathogenesis of a wide range of diseases that involve...
Interleukins are a family of proteins that regulate the maturation, diff- entiation, or activation of cells involved in immunity and inflammation, and...
In addition to their invaluable role in the fight against infection, Toll-Like Receptors (TLRs) in an under- or over-active state can lead to the pathogenesis of disease, making these receptors a key focal point for many research laboratories. In Toll-Like Receptors: Methods and Protocols, experts in the field contribute techniques currently used to study TLRs, their downstream signalling pathways, and their role in the pathogenesis of disease, with sections examining TLR expression and the application of genetic techniques and microarray analysis to TLR research. Written in the...
In addition to their invaluable role in the fight against infection, Toll-Like Receptors (TLRs) in an under- or over-active state can lead to the p...
