The Golgi Apparatus: The First 100 Years traces the first 100 years of Golgi apparatus discovery from the first published accounts from Pavia, Italy in 1898 to the Centenary Celebration in Pavia, Italy in 1998 and into the decade beyond. It is not intended, however, to be a comprehensive survey but rather to present the perspectives of the authors to summarize their contributions over the past 50 years in parallel with the modern era of Golgi apparatus discovery initiated in 1954 and made possible by the advent of the electron microscope. Included are methods of cell fractionation and...

Prefaces tend to be platitudinous and unconducive to perusal. To this hardened Editor, the appearance of the book represents the end of a stamina-testing saga surpassing any past experience. Amongst the numerous authors - a notably eminent bevy - some were angelic and others suffered harassment to produce, amidst day-to-day pressures, an eventual article in the cause of receptor investigation; few took exception to the strong editing that their material underwent. The reader of this book will be interested rather in its aims and ba- ground.- Does it merit a n his bookshelf? The book is not a...

The study of membrane traffic in reconstituted cell-free systems has generated an unprecedented amount of new information on the biochemistry, molecular biology and genetics of membrane-based molecular events that underly normal and abnormal cellular function. Many of the individual steps have now been isolated and dissected in simple systems that permit detailed molecular analyses of transport mechanisms and their regulation. Reconstituted events of intercompartment transport include inter-membrane recognition, and controlled membrane fusion-fission reactions. Among the many advances is the...