Signaling through antigen receptor initiates a complex series of events resulting in the activation of genes that regulate the development, proliferation and differentiation of lymphocytes. During the past few years, rapid progress has been made in understanding the molecular basis of signaling pathways mediated by antigen and cytokine receptors. These pathways involve protein tyrosine kinases which are coupled to downstream regulatory molecules, including small guanine nucleotide binding proteins (e. g. p21'OS), serine threonine kinases (e. g., members of the ERK family), and a large group...
Signaling through antigen receptor initiates a complex series of events resulting in the activation of genes that regulate the development, proliferat...
Leading experts provide the only comprehensive book examining all aspects of immune response and immune-based treatments for HIV infection. Contributions, divided into three sections, discuss basic mechanisms, immunopathogenesis of HIV infection, and immune-based therapies. Researchers thoroughly review vaccine-including prospects of T cell vaccine-and gene therapy for HIV infection. Additional topics include organization of HIV genes, the role of co-receptors in signaling of lymphocytes, and biological response modifiers. This reference is designed for basic and clinical researchers,...
Leading experts provide the only comprehensive book examining all aspects of immune response and immune-based treatments for HIV infection. Contributi...
Since programmed cell death was first described in insects in 1964 and apoptosis was described in 1972, rapid progress has been made in understanding the basic mechanisms and genes regulating programmed cell death and apoptosis. In addition, defects in various genes regulating programmed cell death have been delineated in several experimental models of human diseases. This volume surveys various aspects of these rapidly developing areas of research in programmed cell death/apoptosis. This volume should be of interest to basic immunologists and molecular biologists. The volume begins with a...
Since programmed cell death was first described in insects in 1964 and apoptosis was described in 1972, rapid progress has been made in understanding ...
Advances in biochemistry, cell biology, genome-wide mutagenesis - coupled with molecular technology, including gene microarray and transgenic and knock-out animals - have been instrumental in understanding the cellular processes and molecular pathways of self-tolerance and autoimmune diseases. The molecular definition of these pathways and processes has led to novel treatments for certain auto-immune diseases that are based on the pathogenesis of diseases rather than on broad-spectrum immunosuppression. This book reviews many of these current developments and proposes future novel approaches...
Advances in biochemistry, cell biology, genome-wide mutagenesis - coupled with molecular technology, including gene microarray and transgenic and knoc...
During the past five years major progress has been made in understanding the basic mechanisms of lymphocyte homeostasis and in the developmental relationship between different memory T subsets and their traffic patterns and functional significance. This volume highlights the current concepts of lymphocyte development, factors regulating lymphocyte trafficking and development, and specialized characteristics and functional properties of naive and memory subsets. This volume is divided into three sections. Section I deals with factors that regulate the development and maturation of T cells...
During the past five years major progress has been made in understanding the basic mechanisms of lymphocyte homeostasis and in the developmental relat...
Mechanisms of Lymphocyte Activation and Immune Regulation X Innate Immunity is the proceedings of the Xth International Conference on Mechanisms of Lymphocyte Activation and Immune Regulation: Innate Immunity, held February 6-8, 2004 in Newport Beach, California. It is the tenth volume of its kind to appear in the series Advances in Experimental Medicine and Biology. Topics include toll receptors, dendritic cells, NK cells, and complement receptors.
Mechanisms of Lymphocyte Activation and Immune Regulation X Innate Immunity is the proceedings of the Xth International Conference...
In recent years, major developments have been made in understanding various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires. These include the role of chromatin regulation and nuclear organization in understating the IgH gene regulation. A role and mechanism of DNA repair proteins in somatic hypermutation has been elucidated. Genetic mutation studies have been instrumental in providing insight into some of the mechanisms involved in targeting CSR to various switch DNA regions located upstream of C region genes, especially a role of AID...
In recent years, major developments have been made in understanding various genetic and epigenetic regulatory processes that are critical for the g...
Image classification is one of the most widely used techniques on remote sensing data. Whereas the actual supervised classification of satellite image is a highly automated process, assembling the training data needed for such classification is anything but automatic. Our research has focused on developing a method to extract the training samples for some classes automatically from the data itself by analyzing the discrete fourier transform of the temporal signatures of every class. The multi- temporal data allows us to characterize objects based on their dynamic processes rather...
Image classification is one of the most widely used techniques on remote sensing data. Whereas the actual supervised classification of satellite ima...
Mechanisms of Lymphocyte Activation and Immune Regulation X Innate Immunity is the proceedings of the Xth International Conference on Mechanisms of Lymphocyte Activation and Immune Regulation: Innate Immunity, held February 6-8, 2004 in Newport Beach, California. It is the tenth volume of its kind to appear in the series Advances in Experimental Medicine and Biology. Topics include toll receptors, dendritic cells, NK cells, and complement receptors.
Mechanisms of Lymphocyte Activation and Immune Regulation X Innate Immunity is the proceedings of the Xth International Conference...
Factorial designs were introduced and popularized by Fisher (1935). Among the early authors, Yates (1937) considered both symmetric and asymmetric factorial designs. Bose and Kishen (1940) and Bose (1947) developed a mathematical theory for symmetric priIi't&-powered factorials while Nair and Roo (1941, 1942, 1948) introduced and explored balanced confounded designs for the asymmetric case. Since then, over the last four decades, there has been a rapid growth of research in factorial designs and a considerable interest is still continuing. Kurkjian and Zelen (1962, 1963) introduced a tensor...
Factorial designs were introduced and popularized by Fisher (1935). Among the early authors, Yates (1937) considered both symmetric and asymmetric fac...
