The pathophysiology of sepsis can be regarded as a series of steps, beginning with the invasion of normally sterile tissue by microbes and the elaboration of various pro-inflammatory mediators. The final common pathway is often the development of the multiple organ dysfunction syndrome (MODS). Whereas a great deal has been learned during the past quarter century about the inflammatory processes associated with sepsis (and other related conditions, such as ischemia/reperfusion injury), our understanding is far less developed with respect to the pathophysiological events that lead to organ...
The pathophysiology of sepsis can be regarded as a series of steps, beginning with the invasion of normally sterile tissue by microbes and the elabora...
William J. Sibbald Konrad F. W. Messmer Mitchell P. Fink
Researchers from many disciplines, with both basic and clinical perspectives, came together in this volume to review and debate issues pertaining to the investigation and control of tissue oxygenation in acute medicine, as well as treatments to improve tissue oxygenation when abnormal. In this latter context, special emphasis is placed on understanding the effect of blood substitutes on the circulation and on the potential roles of this family of compounds in clinical medicine.
Researchers from many disciplines, with both basic and clinical perspectives, came together in this volume to review and debate issues pertaining to t...
The pathophysiology of sepsis can be regarded as a series of steps, beginning with the invasion of normally sterile tissue by microbes and the elaboration of various pro-inflammatory mediators. The final common pathway is often the development of the multiple organ dysfunction syndrome (MODS). Whereas a great deal has been learned during the past quarter century about the inflammatory processes associated with sepsis (and other related conditions, such as ischemia/reperfusion injury), our understanding is far less developed with respect to the pathophysiological events that lead to organ...
The pathophysiology of sepsis can be regarded as a series of steps, beginning with the invasion of normally sterile tissue by microbes and the elabora...
Every medical specialty has as its basis a core of classic papers which both reflects the historical background and gives insight into its present and future developments. The selected papers in this volume highlight landmarks in the development of critical care medicine. Internationally acclaimed experts have chosen what they consider to be the most important papers in their respective subspecialties. Each entry follows a set format, starting with the abstract and the reference to the original source of publication. This is followed by analysis of the strengths and weaknesses of the paper...
Every medical specialty has as its basis a core of classic papers which both reflects the historical background and gives insight into its present ...
Although its roots date back to the early decades of the 20th century, critical care medicine did not emerge as a specialty in medicine until the 1970 s. Over the last 30 years or so, the field of critical care medicine has grown tremendously and there is now a solid body of scientific information that forms the foundation for the practice of critical care medicine. But, now as physicians and hospitals around the world focus to an ever greater extend on providing high quality care, the practice of critical care medicine will continue to grow in visibility and importance among...
Although its roots date back to the early decades of the 20th century, critical care medicine did not emerge as a specialty in medicine ...
