This book is an essential anatomical resource for developmental biologists who need to know about any aspect of mouse developmental anatomy, as well as for geneticists using the mouse embryo as a model. The book is a companion to Kaufman's The Atlas of Mouse Development, and details the developmental anatomy of the early embryo, the transitional tissues, and all the major organ systems. It also provides extensive comparisons with human developmental anatomy, both normal and abnormal. The book has extensive reference indexes detailing developmental stage criteria.

The...

Organogenesis of the kidney has been intensely studied for over a century. In recent years advances in molecular techniques have not only made great inroads into exploring the genetic regulation of this complex process but also began to unravel the molecular basis of many forms of congenital kidney disease. This book is a comprehensive study on these findings and the only book available with such in depth coverage of the kidney.

• Hundreds of color figures depicting key events in all aspects of kidney development
• Full coverage of the genetic and cellular basis of kidney...

This volume outlines all of the phases of the gametophytic generation in ferns such as spore germination and sex organ initiation, from how the gametophyte grows to how it eventually initiates the sporophytic generation. The book discusses these stages in morphological, physiological, cytological and biochemical terms, and, by combining all these perspectives, presents a new view of this interesting developmental process that sheds light on general plant development. Developmental biologists will find this book a useful resource.

This comprehensive and cogent survey examines the subject of embryonic determination, the set of processes fundamental to animal development by which cells in the early embryo acquire different developmental capabilities. Examining both the classical literature and the newer, molecular findings, the author summarizes the current state of our understanding of determination and poses key questions for the future. He begins with a consideration of how much spatial pattern is already laid down when the egg forms inside the mother, and ends just before the formation of visible organs. Within these...

This is the first comprehensive review and discussion of meiosis, the antithesis of fertilization. Meiosis is a special form of nuclear division "invented" by sexually reproducing eukaryotes to ensure that a correct chromosome complement is maintained over successive generations. In this masterly treatment, the author describes the scheduling, mechanisms, biochemistry and the genetic control of the events of meiosis in sexual systems as well as the variants adopted by subsexual forms. This will be an essential text for upper division students and research workers in genetics, cytology and...

Examines the genetic circuitry of the 'fruit fly', tackling the hows and the whys behind fly development.

In Neuronal Growth Cones, Phillip Gordon-Weeks explores the molecular biology of the behavior of growth cones, conical-like endings of the growing axon. He covers the basic morphology and behavior of growth cones, motility and neurite extension via the growth cone cytoskeleton, pathfinding, intracellular signaling, and synaptogenesis. A detailed, critical analysis of all aspects of growth cone biology, this incisive reference is an essential work for advanced graduate students, postgraduates, and researchers in cellular and molecular neuroscience, developmental biology, and anatomy.

The central thesis of this book is that Volvox and its unicellular and colonial relatives provide a wholly unrivaled opportunity to explore the proximate and ultimate causes underlying the evolution from unicellular ancestors of multicellular organisms with fully differentiated cell types. A major portion of the book is devoted to reviewing what is known about the genetic, cellular and molecular basis of development in the most extensively studied species of Volvox: V. cateri, which exhibits a complete division of labor between mortal somatic cells and immortal germ cells. However, this topic...

The chapters in this book are centered around the structure of tissues, an intermediate and neglected level between overt morphology and biochemistry, and will be of great interest to all those engaged in attempting to understand the principles behind plant development. The author's purpose is to predict what should be looked for on a molecular level so as to account for observable forms. Each chapter deals with a defined problem such as the role of hormones as correlative agents, tissue polarization, apical meristems and cell lineages. The final chapter develops an alternative approach to...

This book attempts to trace the long history of some of the major ideas in the field and gives an account of our current knowledge of animal cytokinesis. It contains descriptions of division in different kinds of cells, as well as the proposed explanations of the mechanisms underlying the visible events. Experiments devised to test cell division theories are described and explained. The forces necessary to deform animal cells to the degree shown in cytokinesis now appear to originate from the interaction of linear polymers and motor molecules that have roles in force production and in the...