Multiple Sclerosis (MS) is a chronic, often disabling disease that affects more than 400,000 people in the United States. In addition to the physical challenges it poses, MS can have negative emotional effects. Depression, anxiety and stress are common among patients with MS.

This therapist guide provides instruction for delivering treatment to individuals with MS who are experiencing stress and depressed mood. The stress and mood management program described has been developed over more than ten years of research and clinical trials. The treatment is based on cognitive-behavioral therapy...