Naturally occurring RNA always contains numerous biochemically altered nucleotides. They are formed by enzymatic modification of the primary transcripts during the complex RNA maturation process designated RNA modification. A large number of enzymes catalyzing the formation of these modified nucleosides or converting one canonical base into another at the posttranscriptional level have been studied for many years, but only recently have systematic and comparative studies begun. The functions of individual enzymes and/or the modified/edited nucleosides in RNA, however, have remained largely...
Naturally occurring RNA always contains numerous biochemically altered nucleotides. They are formed by enzymatic modification of the primary transcrip...
One of the challenges faced by every cell as well as by whole organisms is to maintain appropriate concentrations of essential nutrient metals while excluding nonessential toxic metals. Toward that end, all organisms have developed mechanisms for metal homeostasis and detoxification to maintain metal levels within physiological limits. This book brings together current knowledge of the molecular basis of metal homeostasis and detoxification in various eukaryotic model systems, including yeasts, plants, and mammals. It focuses on the cellular systems controlling metal transport,...
One of the challenges faced by every cell as well as by whole organisms is to maintain appropriate concentrations of essential nutrient metals whil...
Fungal comparative genomics started in 2000 by the genome sequencing of several yeast species. Since then, over 30 fungal genome sequences have become available. This set represents a huge evolutionary divergence, but also contains closely related genomes. This volume describes how to use this set of genomes to trace events in genome evolution, to extract information about highly conserved and less conserved sequence elements, and to develop novel methods in genomics.
Fungal comparative genomics started in 2000 by the genome sequencing of several yeast species. Since then, over 30 fungal genome sequences have bec...
Naturally occurring RNA always contains numerous biochemically altered nucleotides. They are formed by enzymatic modification of the primary transcripts during the complex RNA maturation process designated RNA modification. A large number of enzymes catalyzing the formation of these modified nucleosides or converting one canonical base into another at the posttranscriptional level have been studied for many years, but only recently have systematic and comparative studies begun. The functions of individual enzymes and/or the modified/edited nucleosides in RNA, however, have remained largely...
Naturally occurring RNA always contains numerous biochemically altered nucleotides. They are formed by enzymatic modification of the primary transcrip...
One of the challenges faced by every cell as well as by whole organisms is to maintain appropriate concentrations of essential nutrient metals while excluding nonessential toxic metals. Toward that end, all organisms have developed mechanisms for metal homeostasis and detoxification to maintain metal levels within physiological limits. This book brings together current knowledge of the molecular basis of metal homeostasis and detoxification in various eukaryotic model systems, including yeasts, plants, and mammals. It focuses on the cellular systems controlling metal transport,...
One of the challenges faced by every cell as well as by whole organisms is to maintain appropriate concentrations of essential nutrient metals whil...
Giving a fresh, substantial and in-depth overview of the topic, this book brings together the latest results in the field of metabolomics. It comprehensively presents the current state of the metabolomics field by underscoring experimental methods, analysis techniques, standardization practices, and advances in specific model systems. As a result, it helps to significantly broaden our perspective on the principles and strategies underpinning this emerging field.
Giving a fresh, substantial and in-depth overview of the topic, this book brings together the latest results in the field of metabolomics. It compr...
