In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading, at that point the largest gain in stock market history. Coming at a time of economic recession and declining technological competitiveness in the United States, the event provoked banner headlines and ignited a period of speculative frenzy over...

InInventing Chemistry, historian John C. Powers turns his attention to Herman Boerhaave (1668 1738), a Dutch medical and chemical professor whose work reached a wide, educated audience and became the template for chemical knowledge in the eighteenth century. The primary focus of this study is Boerhaave s educational philosophy, and Powers traces its development from Boerhaave s early days as a student in Leiden through his publication of the Elementa chemiaein 1732. Powers reveals how Boerhaave restructured and reinterpreted various practices from diverse chemical traditions...

In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading, at that point the largest gain in stock market history. Coming at a time of economic recession and declining technological competitiveness in the United States, the event provoked banner headlines and ignited a period of speculative frenzy over...

During much of the nineteenth century, physicians and pharmacists alike considered medical patenting and the use of trademarks by drug manufacturers unethical forms of monopoly; physicians who prescribed patented drugs could be, and were, ostracized from the medical community. In the decades following the Civil War, however, complex changes in patent and trademark law intersected with the changing sensibilities of both physicians and pharmacists to make intellectual property rights in drug manufacturing scientifically and ethically legitimate. By World War I, patented and trademarked drugs...

During the seventeenth and eighteenth centuries, Europeans raised a number of questions about the nature of reality and found their answers to be different from those that had satisfied their forebears. They discounted tales of witches, trolls, magic, and miraculous transformations and instead began looking elsewhere to explain the world around them. In "The Limits of Matter," Hjalmar Fors investigates how conceptions of matter changed during the Enlightenment and pins this important change in European culture to the formation of the modern discipline of chemistry.
Fors reveals how,...

The advent of recombinant DNA technology in the 1970s was a key moment in the history of both biotechnology and the commercialization of academic research. Doogab Yi s The Recombinant University draws us deeply into the academic community in the San Francisco Bay Area, where the technology was developed and adopted as the first major commercial technology for genetic engineering. In doing so, it reveals how research patronage, market forces, and legal developments from the late 1960s through the early 1980s influenced the evolution of the technology and reshaped the moral and...

William Hyde Wollaston made an astonishing number of discoveries in an astonishingly varied number of fields: platinum metallurgy, the existence of ultraviolet radiation, the chemical elements palladium and rhodium, the amino acid cystine, and the physiology of binocular vision, among others. Along with his colleagues Humphry Davy and Thomas Young, he was widely recognized during his life as one of Britain's leading scientific practitioners in the first part of the nineteenth century, and the deaths of all three within a six-month span, between 1828 and 1829, were seen by many as the end of a...

After World War II, the US Atomic Energy Commission (AEC) began mass-producing radioisotopes, sending out nearly 64,000 shipments of radioactive materials to scientists and physicians by 1955. Even as the atomic bomb became the focus of Cold War anxiety, radioisotopes represented the government's efforts to harness the power of the atom for peace--advancing medicine, domestic energy, and foreign relations. In Life Atomic, Angela N. H. Creager tells the story of how these radioisotopes, which were simultaneously scientific tools and political icons, transformed biomedicine and ecology....

What did it mean to be a scientist before the profession itself existed? Jan Golinski finds an answer in the remarkable career of Humphry Davy, the foremost chemist of his day and one of the most distinguished British men of science of the nineteenth century. Originally a country boy from a modest background, Davy was propelled by his scientific accomplishments to a knighthood and the presidency of the Royal Society. An enigmatic figure to his contemporaries, Davy has continued to elude the efforts of biographers to classify him: poet, friend to Coleridge and Wordsworth, author of travel...

In Inventing Chemistry, historian John C. Powers turns his attention to Herman Boerhaave (1668-1738), a Dutch medical and chemical professor whose work reached a wide, educated audience and became the template for chemical knowledge in the eighteenth century. The primary focus of this study is Boerhaave's educational philosophy, and Powers traces its development from Boerhaave's early days as a student in Leiden through his publication of the Elementa chemiae in 1732. Powers reveals how Boerhaave restructured and reinterpreted various practices from diverse chemical traditions...