In this volume of Reviews there are three outstanding articles, one on phspholipase D, an enzyme that is widely distributed in bacteria, protozoa, fungi, plants and animals. Phospholipase D carries out a transphosphatidylation reaction, which is unique to this enzyme. This review is focussed on mammalian PLDs. The second review deals with endotoxin tolerance, the term which describes the phenomenon that immune responses and metabolic changes are mitigated after repeated LPS administration. The third article summarizes the current knowledge relevant to understanding the molecular basis of GPCR...
In this volume of Reviews there are three outstanding articles, one on phspholipase D, an enzyme that is widely distributed in bacteria, protozoa, fun...
In this volume of Reviews of Physiology we present three articles on modulation of PKC in antitumor treatment, compartment-specific functions of the ubiquitin-proteasome pathway and transgenic models of alpha2-adrenergic receptor subtype function.
In this volume of Reviews of Physiology we present three articles on modulation of PKC in antitumor treatment, compartment-specific functions o...
In this second special issue on signal transduction leading specialists in their fields again present overviews of topics related to the highly topicalsubject of signal transduction. The first contribution, by Keppler, deals with the biosynthesis, transport, inactivation, and analysis of leukotrienes. Mohr et al. present an excellent overview of the biology of the peptide hormone oxytocin and its role in signal transduction.The review by Holzer describes the significance of peptinergic sensory neurons in the control of vascular functions. In the contribution by Wolf etal the molecular biology...
In this second special issue on signal transduction leading specialists in their fields again present overviews of topics related to the highly topica...
