The purpose of this two-volume work is to provide an update on the use of this powerful technology. As such, the books provide an insight in to the techniques for the non-specialist. Scientists embarking upon st udies in chronic lung disease will find a review of the current status of research. At the same time, the books are useful to clinicians, bo th specialist and academic, and to scientists already involved in the basic aspects of the pathogenesis of lung disease. Both volumes deal w ith basic mechanisms of cell biology, receptors and cellactivation and provide an insight as to how the...

This book gives an up-to-date analysis of the epidemiology of asthma i n children and adults, the role of steroids in asthma management and n ew and novel asthma therapies. Specific chapters deal with the epidem iology of asthma mortality and of childhood asthma, others discuss the advantages and drawbacks of the use of b2-adenoreceptor agonists, cor ticosteroids, theophylline and new generation phosphodiesterase inhibi tors in the treatment of asthma. A new non-invasive method to assess a irway inflammation is also presented as well as steroid-sparing therap ies in asthma. The book addresses...

Nitric oxide is an endogenously produced gas with a wide range of biological effects and has been implicated in many physiological and pathophysiological processes. It is released by many cell types in various organs but is particularly important in the maintenance of normal lung function. Nitric oxide in exhaled breath has been identified as a marker for lung disease in some patients. Thus, it is appropriate to consider the lung separately for the role and functioning of nitric oxide. The authors identify key areas in the history, biochemistry, physiology, pathophysiology, immunology and...

This text provides a concise review of the lung's role in the immune system and a detailed account of both primary and secondary lung diseases which are characterized by immunological perturbation or frank autoimmunity. It presents a up-to-date account of disorders ranging from infection to neoplasia and the chapters provide insights into the aetiopathogenesis and clinical features and treatment of immunologically linked pulmonary disease.

Lung cancer is a disease with pandemic public health implications as it is now the leading cause of cancer mortality throughout the world. This book results from two recent International Association for the Study of Lung Cancer (IASLC) Workshops on lung cancer prevention. It strikes a balance between considering public health approaches to tobacco control and population-based screening, advances in clinical evaluation of chemoprevention approaches, and the biology of lung carcinogenesis. Indeed, while the science of smoking cessation is evolving as new pharmacological tools are moving into...

Focussed specifically on children and pediatric respiratory diseases, "The Pediatric Lung+" reviews the current status of pharmacological therapy for asthma, viral pneumonia, cystic fibrosis, bronchopulmonary dysplasia and acute respiratory failure. A review of aerosol delivery systems in children and an up-to-date treatise on mucolytic agents is also included. The chapters are written by leading specialists in the field and summarize the latest developments in pediatric pulmonology, as well as covering a comprehensive range of respiratory diseases in children. Pediatric pulmonologists,...