Epigentic alterations, unlike genetic, are, in principle, amenable to pharmacological intervention, and a few of those drugs are currently undergoing clinical trial. This volume highlights the results of those studies.
Epigentic alterations, unlike genetic, are, in principle, amenable to pharmacological intervention, and a few of those drugs are currently undergoi...
Volume 37 of "Progress in Drug Research" contains seven articles and the various indexes which facilitate its use and establish the connection with the previous volumes. While all articles deal with some of the topical aspects of drug research, the contribution by Al- fred Burger on "Isosterism and bioisosterism in drug design" is of great value to those researchers who are engaged in drug design and wish to include isosteric considerations in establishing a work- ing hypothesis. The remaining six reviews provide an overview of the work in- volved in the search for new and better medicines....
Volume 37 of "Progress in Drug Research" contains seven articles and the various indexes which facilitate its use and establish the connection with th...
Volume 47 of "Progress in Drug Research" contains eight reviews and the various indexes which facilitate its use and establish the connection with the previous volumes. The articles in this volume deal with inotropic steroids, with chemokines and their involvement in a wide range of inflam- matory diseases, with the subclassification and nomenclature of ul- and Uz-adrenoceptors, with Chinese traditional medicine, with drug targets in the molecular pathogenesis of asthma, with cytokines and their therapeutic application in immunosuppression and immunostimulation, with alter- native medicine...
Volume 47 of "Progress in Drug Research" contains eight reviews and the various indexes which facilitate its use and establish the connection with the...
This series was founded in 1959, and its focus has shifted from medicinal chemistry to a much wider scope. It now encompasses all fields concerned with the development of therapeutic drugs and the elucidation of their mechanisms of action, reflecting the increasingly complex nature of modern drugs research. Invited authors write reviews on the following fields: biology, chemistry, biochemistry, physiology, immunology, pharmacy, toxicology, pharmacology, and clinical aspects. The books are linked by indexes in each volume, forming an almost encyclopaedic work.
This series was founded in 1959, and its focus has shifted from medicinal chemistry to a much wider scope. It now encompasses all fields concerned wit...
Founded in 1959, the series has moved from its initial focus on medicinal chemistry to a much wider scope. This volume encompasses all fields concerned with the development of therapeutic drugs, and the elucidation of their mechanisms of action. When combined with the other volumes, it serves as a time-saving source of information for researchers concerned with drug research, and all those who need to keep abreast of ongoing developments in medicines.
Founded in 1959, the series has moved from its initial focus on medicinal chemistry to a much wider scope. This volume encompasses all fields concerne...
This volume covers a range of topics including caco-2 cell permeability versus human gastrointestinal absorption - QSPR analysis; pharmacology of appetite supression; serotonin, dopamine and norepinephrine transporters in the central nervous system and their inhibitors; neuropeptides in drug research; regulation of NMDA receptors by ethanol; and troglitazone and emerging glitazones - new avenues for potential therapeutic benefits beyond glycemic control and applications of developmental biology to medicine and agriculture.
This volume covers a range of topics including caco-2 cell permeability versus human gastrointestinal absorption - QSPR analysis; pharmacology of appe...
From the contents: A- C. Brater and M. D. Murray: The effects of NSAIDs on the kidney A- G. Edwards and A. H. Weston: Latest developments in potassium channel modulator drugs A- M.R. Juchau and Y. Huang: Chemical teratogenesis in humans: Biochemical and molecular mechanisms A- S.P. Gupta: Studies on cardiovascular drugs A- G. Polak: Antifungal chemotherapy: An everlasting battle A- O. Valdenaire: New insights into the bioamine receptor family
From the contents: A- C. Brater and M. D. Murray: The effects of NSAIDs on the kidney A- G. Edwards and A. H. Weston: Latest developments in potassium...
Systems biology is an emerging discipline that studies the underlying network structure and the dynamics of metabolism, cells or whole organisms. It aims to investigate all interacting components simultaneously and requires data from high throughput techniques. These data from the "omic" sciences are computed and used to build in silico models of biological systems that ultimately will prove to be an invaluable tool in drug development.
This book brings together the various fields of functional genomics and systems biology that provide information on metabolic function with a...
Systems biology is an emerging discipline that studies the underlying network structure and the dynamics of metabolism, cells or whole organisms. I...
