This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological regulation of cellular functions will be explored, as well as applications to pathophysiological states in disease.
This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. An integrative approach across different scales f...
In this book, leading figures in the field of Developmental Origins of Health and Disease provide up-to-date information from human clinical trials, cohorts, and animal physiology experiments to reveal the interdependence between parental obesity and health of the offspring. Obesity of the mother and father produces obesity in their offspring, so we are caught up in an intergenerational cycle, which means that even our children's future health is in peril. This book gives a timely and much-needed synthesis of the mechanisms, potential targets of future interventions, and the challenges...
In this book, leading figures in the field of Developmental Origins of Health and Disease provide up-to-date information from human clinical trials...
This book presents cutting edge methods that provide insights into the pathways by which salt and water traverse cell membranes and flow in an orchestrated fashion amongst the many compartments of the body. It focuses on a number of molecular, cellular and whole animal studies that involve multiple physiological systems and shows how the internal milieu is regulated by multifactorial gene regulation, molecular signaling, and cell and organ architecture.
Topics covered include: water channels, the urinary concentrating mechanism, angiotensin, the endothelin system, miRNAs and MicroRNA...
This book presents cutting edge methods that provide insights into the pathways by which salt and water traverse cell membranes and flow in an orch...
This book sheds new light on the physiology, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the basic cellular models and functions by means of a compelling clinical perspective, addressing aspects from the laboratory bench to the bedside. The individual chapters, written by leading scientists and clinicians, explore specific ion channels and transporters located in the epithelial tissues of the kidney, intestine, pancreas and respiratory tract, all of which play a crucial part in maintaining homeostasis. Further topics include the fundamentals...
This book sheds new light on the physiology, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the basic ...
This book sheds new light on the molecular mechanisms that generate circadian rhythms. It examines how biological rhythms influence physiological processes such as sleep, hormone synthesis and secretion, immunity, kidney function, the cardiovascular system, blood pressure, and the digestive system.
This book sheds new light on the molecular mechanisms that generate circadian rhythms. It examines how biological rhythms influence physiological proc...
Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury (SCI). This book will present comprehensive information on the unique physiologic effects of SCI and the potential role of exercise in treating and mitigating these effects.
Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury (SCI). This book will present comprehensive information o...
The complex microbial communities that inhabit most external human surfaces play a key role in health and diseases. Thus, this book will further highlight the application of organoids in studying microbiome in the context of health and disease, focusing on mechanistic concepts that underlie the complex relationships between host and microbes.
The complex microbial communities that inhabit most external human surfaces play a key role in health and diseases. Thus, this book will further highl...