The estimated prevalence of erectile dysfunction (ED) ranges from 15 - 50 million men in the United States alone, with all age groups of men affected. Despite still-existing taboos surrounding male impotence, more men are seeking help and treatment with the advent of newer treatment options in recent years, most notably oral PDE-5 inhibitors that shed light on the primary vascular cause and treatment target in most cases. In the majority of men, ED has a physical cause and can be effectively treated. Increased knowledge of cause and treatment options, however, requires clinicians to become...