Human neurological and neuromuscular disorders caused by nucleotide expansion are the focus of growing interest of practicing physicians and of interested biomedical researchers. This volume represents a comprehensive and up-to-date description of many of the better-studied disorders. The authors discuss molecular, clinical and pathological aspects of the diseases as well as our current understanding of their underlying mechanisms.
Human neurological and neuromuscular disorders caused by nucleotide expansion are the focus of growing interest of practicing physicians and of int...
This book presents applications of bioinformatics tools that experimental research scientists use in "daily practice." Its interdisciplinary approach combines computational and experimental methods to solve scientific problems. The book begins with reviews of computational methods for protein sequence-structure-function analysis, followed by methods that use experimental data obtained in the laboratory to improve functional predictions.
This book presents applications of bioinformatics tools that experimental research scientists use in "daily practice." Its interdisciplinary approa...
Extracellular nucleic acids have emerged as important players in the fields of biology and the medical sciences. This book covers the developing fields related to extracellular nucleic acids, including those of basic biology, ecology and the medical sciences, and provides readers with the knowledge on them.
Extracellular nucleic acids have emerged as important players in the fields of biology and the medical sciences. This book covers the developing field...
The development of agents capable of cleaving RNA and DNA has attracted considerable attention from researchers in the last few years, because of the immediate and very important applications they can find in the emerging fields of biotechnology and pharmacology. There are essentially two classes of these agents - nucleases that occur naturally inside cells and synthetically produced artificial nucleases. The first class includes protein enzyme nucle ases and catalytic RNA structured ribozymes that perform cleavage of the phosphodiester bonds in nucleic acids according to a hydrolytic pathway...
The development of agents capable of cleaving RNA and DNA has attracted considerable attention from researchers in the last few years, because of the ...
Mitochondrial DNA is one of the most closely explored genetic systems, because it can tell us so much about the human past. This book takes a unique perspective, presenting the disparate strands that must be tied together to exploit this system. From molecular biology to anthropology, statistics to ancient DNA, this first volume of three presents a comprehensive global picture and a critical appraisal of human mitochondrial DNA variation.
Mitochondrial DNA is one of the most closely explored genetic systems, because it can tell us so much about the human past. This book takes a uniqu...
Editing a book on editing has a certain tongue in cheek connotation to it, and I must admit that I was not aware what the job truly entailed when the project started. However, over the many months that it took to complete the book, it was interesting to realize that indeed printing-type editing and biological editing have many matching characteristics. Therefore, the quote by the well-known ? lm editor Verna Fields (1918 1982), I wish the word editing had never been invented, editing implies correcting, and it s not, can function as a motto for the book: the various biological phenomena that...
Editing a book on editing has a certain tongue in cheek connotation to it, and I must admit that I was not aware what the job truly entailed when the ...
A review of the pre- and postnatal development in the North American opossum (Didelphus Virginiana). Volume One summarizes areas such as fertilization, blastocyst formation and early organogenesis, foetal membranes and placentation, blood and blood-forming organ and cardiovascular system.
A review of the pre- and postnatal development in the North American opossum (Didelphus Virginiana). Volume One summarizes areas such as fertilization...
Providing the reader with an introduction to state-of the-art concepts and methods in the rapidly advancing field of protein engineering, this book will be of use to anyone interested in the study of proteins, in academia as well as in industry.
Providing the reader with an introduction to state-of the-art concepts and methods in the rapidly advancing field of protein engineering, this book wi...
Human neurological and neuromuscular disorders caused by nucleotide expansion are the focus of growing interest of practicing physicians and of interested biomedical researchers. This volume represents a comprehensive and up-to-date description of many of the better-studied disorders. The authors discuss molecular, clinical and pathological aspects of the diseases as well as our current understanding of their underlying mechanisms.
Human neurological and neuromuscular disorders caused by nucleotide expansion are the focus of growing interest of practicing physicians and of int...
It is generally accepted that neuropsychiatric disorders have a biological basis. Pathological changes leading to illness have been confirmed for Alzheimer s (amyloid plaques) and Parkinson s disease (loss of dopaminergic transmission) and are the foundation for studies on the molecular biology of these disorders. For other neuropsychiatric disorders, in particular for schizophrenic and affective disorders, molecular causes appear to be more complex and therefore remain hypothetical, despite decades of research. Changes in a number of neuronal pathways and structures have been reported to...
It is generally accepted that neuropsychiatric disorders have a biological basis. Pathological changes leading to illness have been confirmed for A...