This second edition expands on the previous volume by incorporating state-of-the-art electrophysiological and anatomical methods and their application to the study of several systems of the brain involved in a range of functions. Chapters in this edition cover topics such as the value and difficulty of multi-site recordings using depth or surface electrodes; an assessment of different electrophysiological techniques used in non-human animals and humans; applying single-unit and ensemble recordings to the study of temporal dynamics in cognition; approaches to electroencephalography (EEG)...
This second edition expands on the previous volume by incorporating state-of-the-art electrophysiological and anatomical methods and their applic...
This second edition volume expands on the previous edition with updated descriptions on different computational methods encompassing ligand-based, structure-based, and combined approaches with their recent applications in anti-Alzheimer drug design. Different background topics like recent advancements in research on the development of novel therapies and their implications in the treatment of Alzheimer’s Disease (AD) have also been covered for completeness. Special topics like basic information science methods for insight into neurodegenerative pathogenesis, drug repositioning and...
This second edition volume expands on the previous edition with updated descriptions on different computational methods encompassing ligand-based...
This volume discusses the latest techniques used in the diverse fields of single cell ‘omics and covers topics such as quantifying the single cell transcriptome; isolation of cells in nanoliter volumes for single cell proteomics measurements by nano-LC-MS/MS; and single cell protein characterization by immunoblotting. A wide range of methodologies are highlighted, ranging from high-yield chemical amplification to mass spectrometry and nanotechnology for the analysis of the chemical constituents of cells. In the Neuromethods series style, chapters include both in-depth overviews,...
This volume discusses the latest techniques used in the diverse fields of single cell ‘omics and covers topics such as quantifying the single cel...
Recent developments in lesion-symptom mapping (LSM) have spurred rapid growth. This volume provides comprehensive coverage of the steps and considerations involved in LSM. The chapters cover the definition and types of brain lesions, how to prepare them for analysis, standard LSM methods, network-based LSM methods, and approaches of transient lesions induced by brain stimulation. These chapters are supplemented by practical, hands-on mini tutorials on implementing the different analyses using freely-available software. In the Neuromethods series style, chapters include the kind of...
Recent developments in lesion-symptom mapping (LSM) have spurred rapid growth. This volume provides comprehensive coverage of the steps and consi...
This volume explores the latest techniques used to study neurodevelopmental diseases (NDD) that range from molecular aspects to integrated research approaches and brain imaging in living rodents. Chapters in this book cover topics such as protocols to deliver shRNA in vitro and in vivo using lentiviral particles to knock-down specific protein expression; experimental procedures to use recombinant fluorescent probes to visualize endogenous proteins at the mammalian synapse; CRISPR/Cas9 toolkit to assess either gain- or loss-of-gene function in brain organoids; detailed protocols to use in...
This volume explores the latest techniques used to study neurodevelopmental diseases (NDD) that range from molecular aspects to integrated research...
This volume covers the latest research and development in the areas of Vagus Nerve Stimulation (VNS) as it relates to bioelectronic medicine from neonate to adult. The chapters in this book cover topics such as invasive and non-invasive VNS including methodological considerations (study design, stimulation parameters, and use of heart rate variability metrics); mechanisms of action (automatic regulation and immune plasticity); and disorders where VNS approaches may be therapeutic (migraine and cluster headaches, mood disorders, trauma-related disorders, and language learning). In the...
This volume covers the latest research and development in the areas of Vagus Nerve Stimulation (VNS) as it relates to bioelectronic medicine from n...
This volume looks at the framework in which different scientific disciplines are integrated into the latest studies in behavioral neurogenetics, and covers new approaches toward understanding the system that controls behavior across the animal kingdom. Chapters in this book cover topics such as mapping brain-wide mesoscale connectome from single animals with BRICseq; gut microbes and Drosophila behavior; bioassaying the function of pheromones in Drosophila melanogaster’s social behavior; automated behavior analysis using a YOLO-based object detection system; and proteomic...
This volume looks at the framework in which different scientific disciplines are integrated into the latest studies in behavioral neurogenetics, ...
This volume explores the latest eye-tracking methodologies that help researchers understand the background, methods, and applications involved in these studies. The chapters in this book cover topics such as methods and models of eye-tracking in natural environments; natural gaze informatics (i.e., assisted wheelchair mobility); eye-tracking application to understand the visual control of locomotion; eye movement in neurological disorders; and eye movements in sports research and practice. In the Neuromethods series style, chapters include the kind of detail and key advice from...
This volume explores the latest eye-tracking methodologies that help researchers understand the background, methods, and applications involved in...
This volume provides current state-of-the-art methods for screening, diagnosis, management, and prevention of fetal alcohol spectrum disorder (and FASD). Chapters detail animal models, mechanism of ethanol teratogenesis, genetic mechanisms, clinical perspectives, physical traits in children with FASD, managing behavior, FASD and the correction system, nutritional influences aiding FASD prevention, prenatal alcohol screening, the use of dental signatures in FASD diagnosis, the experiences of FASD research and clinical practices in Australia, Canada, UK, USA, adult FASD diagnosis, FASD and...
This volume provides current state-of-the-art methods for screening, diagnosis, management, and prevention of fetal alcohol spectrum disorder (and ...
This volume looks at the latest advancements used by researchers to study psychophysiology and cognitive neurosciences. The chapters in this book cover topics such as classical event-related brain responses (P300, MMN, and CNV); anatomical structures and physiological mechanisms underlying the capability of feeling pain and smelling; magnetoencephalography (MEG); and brain-computer interface techniques using electrical activity generated by the brain. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get...
This volume looks at the latest advancements used by researchers to study psychophysiology and cognitive neurosciences. The chapters in this...
