Providing a broad overview of basic and clinical aspects of alpha 1-antitrypsin (a 1AT) deficiency, this up-to-date reference discusses the complex pathobiological processes underlying the pathogenesis of a1AT deficiency, describes the a1AT gene and its promoter, and details specific therapies to prevent the major clinical manifestations of the disorder.

Since the publication of Sleep Apnea: Diagnosis and Treatmen - First Edition there have been many significant changes within the field of sleep disorders. This source will highlight the changes in the field of sleep apnea while examining new treatment techniques, new treatment data, and emerging data that relates to specific disorders.

Once considered an experimental therapy, lung transplantation is now regarded as a viable treatment option for selected patients with end-stage lung diseases. As more and more of these cases arise, it becomes imperative for those involved in the care of lung transplant patients to have a vast understanding of the multidiscipline process of lung transplantation. This text provides a comprehensive overview of this process covering everything from the history of the lung transplant program to the long term effects of the procedure.

Written by skilled specialists in the field of interventional pulmonology, the new second edition thoroughly explores the latest advancements, newest therapies, and diagnostic techniques in interventional pulmonary medicine.