In this book the pathophysiology, diagnosis, and therapy of most aspects of peptic ulcer disease are examined in detail. Covered are the pharmacology of the parietal cell and the latest hypotheses for the development of acid-peptic disease including epidermal growth factor, gastrin and other peptide hormones, fatty acids and prostaglandins, helicobacter pylori, and gastric acid hypersecretion including Zollinger-Ellison syndrome. The book also deals with the newer antisecretory medication such as omeprazole with a review of H2-receptor antagonists. Rounding off the subject are chapters on...
In this book the pathophysiology, diagnosis, and therapy of most aspects of peptic ulcer disease are examined in detail. Covered are the pharmacology ...
The chapters in this volume describe a powerful emerging approach for the therapy of disease. Targeted drug delivery, that is control of the kinetic behavior, tissue distribution, and subcellular localization of pharmaco- logically active agents, offers an important means for improving the efficacy of a wide variety of drug therapies. This is particularly true for therapeutic approaches based on newer agents which are the products of recombinant DNA research. These agents, be they peptides, proteins, or oligonucleotides, tend to be larger, more complex, and less stable than traditional drugs....
The chapters in this volume describe a powerful emerging approach for the therapy of disease. Targeted drug delivery, that is control of the kinetic b...
The subject of this volume is to review chemical agents which affect blood and blood-forming organs. Significant ad- vances made over the past several years in the purification of several hematopoietic growth factors, such as erythro- poietin and colony stimulating factor; the availability of several other growth factors, such as the interleukins which are important in regulating the production of red blood cells, leukocytes, megakaryocytes and platelets are discus- sed. Numerous toxic chemical substances are being produced in our environment which people are exposed todaily causing a...
The subject of this volume is to review chemical agents which affect blood and blood-forming organs. Significant ad- vances made over the past several...
Major advances have been made in the understanding of the molecular mechanisms of atherosclerosis, the disease that still affects more than 50 percent of the population in the highly industrialized countries. This volume covers the most recent advances in the treatment of hyperlipidemia. It represents a necessary update because molecular mechanisms of atherogenesis have been discovered in the past few years and their molecular mechanisms of action identified. Extensively treated are the molecular mechanisms of disease etiology of arteriosclerosis in relation to the major risk factor...
Major advances have been made in the understanding of the molecular mechanisms of atherosclerosis, the disease that still affects more than 50 percent...
Die in der chemischen, biologischen, physiologisch-pharmakologischen und klinischen Literatur zeitlich und raumlich weit verstreuten Beobachtungen und experimentellen Ergebnisse lieen eine Berucksichtigung der Entwicklung der Androgenforschung geboten erscheinen, die von der Mitte des 19. Jahrhunderts bis zur Gegenwart reicht und in keinem ihrer Teilgebiete als abgeschlossen be- trachtet werden kann. Der weite Umfang des Tatsachenmaterials aus sehr verschiedenen Disziplinen der naturwissenschaftlichen und medizinischen Forschung machte eine Auf- teilung unter einer groeren Zahl von...
Die in der chemischen, biologischen, physiologisch-pharmakologischen und klinischen Literatur zeitlich und raumlich weit verstreuten Beobachtungen und...
In the beginning of this century physiology witnessed the creation of a new concept, the hormonal regulation of the work of the digestive organs. It was found that such essential functions as the flow of pancreatic juice and emptying of bile into the intestine were regulated by two hormones, secretin and cholecystokinin, respectively. Already in 1925 French authors attempted to measure the functional capacity of the exocrine pancreas by means of stimulation with secretin. The use- fulness of the secretin test in this connection was definitely established by Scandinavian workers in the 1930's....
In the beginning of this century physiology witnessed the creation of a new concept, the hormonal regulation of the work of the digestive organs. It w...
The literature on co-trimoxazole (TMP jSMX) is voluminous, but in the main it consists of research reports. The same can be said of various symposia that have appeared. This volume attempts to present the current status of this antibacterial combination in a series of topical reviews, each of which represents a comprehensive summary of a segment of the field. The editor acknowledges with appreciation the help provided by JACKIE, JENKS, LEE KUYPER, and particularly, RUTH Ross in the preparation of the Subject Index, and thanks Burroughs Wellcome Co. for providing access to library and word...
The literature on co-trimoxazole (TMP jSMX) is voluminous, but in the main it consists of research reports. The same can be said of various symposia t...
The resolution of links between exposure to components of our complex environmental and causation of reproductive effects in the population constitutes an important problem in the field of toxicology. The focus of this volume is developmental toxicology, which represents one aspect of reproductive toxicology dealing with the study of adverse effects on the developing conceptus. Developmental toxicology, which includes teratogenesis as one of its manifesta- tions, provides a fertile field for research in several basic and clinical disciplines; this field also receives input from several...
The resolution of links between exposure to components of our complex environmental and causation of reproductive effects in the population constitute...
It is quite amazing that the oldest group of medically useful antibiotics, the p-Iactams, are still providing basic microbiologists, biochemists, and clinicians with surprises over 50 years after Fleming's discovery of penicillin production by Penicillium. By the end of the 1950s, the future of the penicillins seemed doubtful as resistant strains of Staphylococcus aureus began to increase in hospital populations. However, the development of semisynthetic penicillins provided new structures with resistance to penicillinase and with broad-spectrum activity. In the 1960s, the discovery of...
It is quite amazing that the oldest group of medically useful antibiotics, the p-Iactams, are still providing basic microbiologists, biochemists, and ...
