The demand for selective organic reactions is growing more acute everyday. Indeed, greater product selectivity has an important impact on energy and resource utilization, in terms of reduced process energy requirements for product separation and purification, in terms of low-value by-products, and in terms of environmental acceptance and compatibility. Moreover, more and more chemicals, especially pharmaceuticals, have to be sold in an optically active form. The search for selectivity constitutes a tremendous challenge for the chemists. In the last two decades, homogeneous transition metal...

If a book needs a third edition, because the previous ones are sold out, one may well question whether an introduction is necessary. However, the Structure of European Industry was meant to be a flexible book, keeping it in tune with actual developments in the European Community. Some explanation is therefore required. Two new chapters on the services industry have been included, to recognize the growing importance of what is fundamentally a bundle of industries. It is also increasingly acknowledged, that the motorcar industry, for its efficiency and innovativeness, is very much dependent on...

P.P. Wong ABSTRACT Tourism is environmentally dependent. The unique character ofcoastal areas gives rise to a distinctive tourist development. Although accounts on the impacts ofcoastal tourism can be found in works relating to tourism in general, there are few works specifically on coastal tourism. This present volume focuses on the physical environment of coastal tourism, particularly the geomorphological aspects. The papers deal with basic aspects of the coastal environment for tourism, methodologies for assessing the coastal environment for tourism and empirical studies of various types...

I became interested in Random Vibration during the preparation of my PhD dissertation, which was concerned with the seismic response of nuclear reactor cores. I was initiated into this field through the cla.ssical books by Y.K.Lin, S.H.Crandall and a few others. After the completion of my PhD, in 1981, my supervisor M.Gera.din encouraged me to prepare a course in Random Vibration for fourth and fifth year students in Aeronautics, at the University of Liege. There was at the time very little material available in French on that subject. A first draft was produced during 1983 and 1984 and...

Among the multiple, subliminal passions that inspire our life in innumerable ways, literature shows us one that seems to play a particularly penetrating role in human concerns. This passion, which Tymieniecka calls an esoteric passion', finds its projection and crystallization in space: it is the esoteric passion for space.
This subliminal passion, investigated through literature, allows the philosopher to reach beneath the fallacious separations of nature, humanness and the cultural world, restoring the wholeness of experience that has become lost in the artificial...

From somewhat enigmatic beginnings 40 years ago, guanylate cyclase research has emerged to occupy a position of prominence in the study of signal transduction. Guanylate cyclase has several intriguing features, including existence in two major forms, membrane and soluble, each independently regulated by distinct mechanisms. The membrane form gives rise to a fascinating signal transduction story important to both peptide hormones and sensory neurons. This volume covers the evolution of the field, peptide hormone receptor work, membrane guanylate cycles, related retinal diseases, and the...

A veritable mountain of literature has been published showing the causal relationship of reactive oxygen/nitrogen species in human disease conditions, and there has been an explosion in the understanding of oxidative stress, the protective role of antioxidants and molecular events involved in the regulation of transcription, editing, and translation of key events leading to disease processes. Strategies need to be developed for prevention of diseases by allowing scientists and clinicians to obtain information on new and emerging advances. The molecular mechanisms involved in several diseases...

It is well established that cellular lipid binding proteins serve central roles in cellular lipid uptake and metabolism. Evidence has been presented that various metabolic diseases, such as hyperlipidemia, atherosclerosis, insulin resistance, and diabetes, are characterized by malfunctioning or deficiencies in cellular lipid binding proteins. For better understanding of the action of lipids as signaling compounds and the role of lipids in intermediary metabolism, it is essential to have detailed knowledge of the interactions between lipids and their cognant binding proteins. In view of this...

Cardiac cell biology has come of age.
Recognition of activated or modified signaling molecules by specific antibodies, new selective inhibitors, and fluorescent fusion tags are but a few of the tools used to dissect signaling pathways and cross-talk mechanisms that may eventually allow rational drug design. Understanding the regulation of cardiac hypertrophy in all its complexity remains a fundamental goal of cardiac research. Since the advancement of adenovirally mediated gene transfer, transfection efficiency is no longer a limiting factor in the study of cardiomyocytes. A limiting...