The purpose of this book is to provide reviews of various antibiotic topics which will be of interest to practising clinicians and to microbiologists. It is hoped that enough references have been provided to enable the enthusiast to immerse himself in the source literature. No attempt has been made to cover the whole field, which is well catered for in the numerous works on the subject. Rather, the intention has been to select a number of topics in which there has been a great deal of change in recent years, and to ask an appropriate authority to review the subject. Since I chose the topics,...

In this volume I have attempted to cover the more important aspects of immunosuppressive therapy. In doing this, I have been very fortunate in securing the help of the distinguished authors who have contributed the chapters that follow and I am grateful to them for providing such thorough and up-to-date accounts of their subjects. Immunosuppression can be mediated by many hundreds of agents and it has been difficult to strike a balance between the 'small print' of drug action in animals and the useful- ness or otherwise of drugs and other agents for inducing immunosuppression in patients. The...

The past few years have seen the publication of a large number of articles and not a few books on the subject of relief of intractable pain.

In the past few years there has been a great upsurge of interest in the problem of essential hypertension. This has been stimulated by several comparatively recent advances, the most important being the demon- stration that many if not most of the cOInplications of hypertension can be prevented with adequate and effective medical treatment. Because of the extremely high prevalence of hypertension (roughly one in six or seven adults) effective preventive treatment will have a tremendous im- pact on national health and longevity. This new approach to the problem of hypertension differs markedly...