Bruce R. Smoller, md, concisely reviews for practitioners and students alike the science of immunopathology, its many basic laboratory tools, and their multiple diagnostic uses in actual clinical case studies. The author presents in an easily digestible form a dictionary of antibody probes, summarizing for each antibody the targeted antigen and its cellular function, its diagnostic utility, and, when available, its sensitivities and specificities for identifying various neoplasms. Real clinical cases from the author's practice demonstrate the benefits of immunopathology.
Bruce R. Smoller, md, concisely reviews for practitioners and students alike the science of immunopathology, its many basic laboratory tools, and thei...
Gene expression studies have revealed diagnostic profiles and upregulation of specific pathways in many solid tumors. The explosion of new information in gene expression profiling could potentially lead to the development of tailored treatments in many solid tumors. In addition many studies are ongoing to validate these signatures also in predicting response to hormonal, chemotherapeutic and targeted agents in breast cancer as well as in other tumors.
Diagnostic, Prognostic and Therapeutic Value of Gene Signatures provides readers a useful and comprehensive resource...
Gene expression studies have revealed diagnostic profiles and upregulation of specific pathways in many solid tumors. The explosion of new informat...
Biotargets of Cancer in Current Clinical Practice presents an updated and reasoned review of the current status of knowledge concerning the major cancer types with a special focus on the current biomarkers, genes involved and the potential future targets of innovative therapies. The volume includes for each major cancer type, a comprehensive although concise discussion of epidemiology, affirmed and innovative biomarkers for diagnosis, and descriptions of the relevant genes for prognosis and (individualized) therapy through biotarget-specific new molecular treatments, with the latest...
Biotargets of Cancer in Current Clinical Practice presents an updated and reasoned review of the current status of knowledge concerning the maj...
In this volume Dr Hui has brought together a comprehensive overview of gestational trophoblastic disease that includes all the currently recognized entities: complete and partial hydatidiform moles, placental site trophoblastic tumor, epithelioid trophoblastic tumor, gestational choriocarcinoma, persistent gestational trophoblastic neoplasia, placental site nodule and exaggerated placental site reaction. Each entity is reviewed in detail, with emphasis on genetic background, clinical presentation, pathologic findings and ancillary studies, differential diagnosis and clinicopathological...
In this volume Dr Hui has brought together a comprehensive overview of gestational trophoblastic disease that includes all the currently recognized en...
Cardiac tumors were once a nosographic entity of scarce clinical interest because of the rarity and of the intrinsic diagnostic and therapeutic impossibilities, and were considered a fatal morbid entity. It has now become a topical subject due to advances in clinical imaging (echo, magnetic resonance, computed tomography) as well as innovation in technologies of in-vivo diagnosis. Cardiac Tumor Pathology presents a spectacular example of these advances with clinico-pathologic correlations. This timely volume covers history, epidemiology, demographics, clinical diagnosis, pathology, imaging by...
Cardiac tumors were once a nosographic entity of scarce clinical interest because of the rarity and of the intrinsic diagnostic and therapeutic imposs...
Skin Cancer: A Practical Approach presents a comprehensive and up to date overview on skin cancer. With an emphasis on practical aspects that will set the basis for guidelines of treatment, the volume presents different diagnostic tools to help physicians obtain the proper diagnosis.
Written by a worldwide base of experts selected on their recognized expertise on the different themes discussed, Skin Cancer: A Practical Approach is a valuable resource for investigators in the field of skin cancer, including pathologists, medical and surgical oncologists, dermatologists,...
Skin Cancer: A Practical Approach presents a comprehensive and up to date overview on skin cancer. With an emphasis on practical aspects tha...
Practicing specialists in pathology, laboratory medicine, and obstetrics comprehensively summarize the latest scientific findings and their experiences in the use and interpretation of laboratory testing in patients who are pregnant or experiencing recurrent pregnancy loss. Topics of interest include the effects of normal physiological changes on test results, test selection for diagnosis, changes in reference ranges, monitoring the pregnant patient, new technologies, and the limitations of laboratory testing. The authors not only clearly explain currently used test methods and technologies...
Practicing specialists in pathology, laboratory medicine, and obstetrics comprehensively summarize the latest scientific findings and their experience...
This volume provides a comprehensive, state-of-the art review in the field of experimental and human nephrogenesis. The book reviews new data on the effects on kidney development by neonatal asphyxia, obstructive uropathies, nephrotoxic drugs, malnutrition, underfeeding, overfeeding and provides all possible preventive measures to ensure the well-being of the kidney at birth. The book also discusses the possible implications between renal development and the insurgence of kidney disease in adult life and the correlation with renal carcinogenesis.
Written by well recognized experts...
This volume provides a comprehensive, state-of-the art review in the field of experimental and human nephrogenesis. The book reviews new data on th...
Well-Differentiated Malignancies: New Perspectives is devoted to an important topic in surgical pathology which is inadequately covered by currently available books. Well-differentiated malignancies are systematically addressed with an emphasis on the tissue/cell specific malignant atypia. The key features for each malignancy are extensively illustrated with high quality pictures from authoritative sources.
This book represents a daring and rarely attempted endeavor to bridge the gap between histopathology and molecular medicine in that cutting-edge molecular findings are...
Well-Differentiated Malignancies: New Perspectives is devoted to an important topic in surgical pathology which is inadequately covered by c...
This volume provides readers a comprehensive and state-of-the-art overview about the range of applications of targeted therapies for solid tumors. The sections of the book have been structured to review the oncogene addicted tumors, the pharmacology and clinical development of new molecularly targeted agents, the use of biomarkers as prognostic, predictive and surrogate endpoints, and the evaluation of tumor response and specific malignancies treated with targeted agents. The book also covers some of the newest developments in cancer therapy that are not adequately covered by any current...
This volume provides readers a comprehensive and state-of-the-art overview about the range of applications of targeted therapies for solid tumors. ...
