This book contains the latest material in the subject, covering next generation sequencing (NGS) applications and meeting the requirements of a complete semester course. This book digs deep into analysis, providing both concept and practice to satisfy the exact need of researchers seeking to understand and use NGS data reprocessing, genome assembly, variant discovery, gene profiling, epigenetics, and metagenomics. The book does not introduce the analysis pipelines in a black box, but with detailed analysis steps to provide readers with the scientific and technical backgrounds required to...

This book contains the latest material in the subject, covering next generation sequencing (NGS) applications and meeting the requirements of a complete semester course. This book digs deep into analysis, providing both concept and practice to satisfy the exact need of researchers seeking to understand and use NGS data reprocessing, genome assembly, variant discovery, gene profiling, epigenetics, and metagenomics. The book does not introduce the analysis pipelines in a black box, but with detailed analysis steps to provide readers with the scientific and technical backgrounds required to...

This book has fundamental theoretical and practical aspects of data analysis, useful for beginners and experienced researchers that are looking for a recipe or an analysis approach. Since R has many packages, even experienced researchers look for how particular functions are used in an analysis workflow.

The main objective of this book is to deliver a comprehensive and insightful account of applying mathematical modelling approaches to very large biological systems and networks, a fundamental aspect of computational systems biology. Several key modelling paradigms will be discussed in detail.

- The first concise textbook on the topic of physiological circuits, it provides basic principles or ‘laws’, and then derives why physiology is built the way it is, and why certain diseases happen while others don’t. - By the end of the book you will be able to use simple but powerful mathematical models to describe physiological circuits, turning details into useful understanding and new ways of thinking about treating diseases, including diabetes, autoimmune diseases, and age-related diseases such as lung fibrosis and cancer. The book explores (i) hormone circuits, (ii) immune...

- The first concise textbook on the topic of physiological circuits, it provides basic principles or ‘laws’, and then derives why physiology is built the way it is, and why certain diseases happen while others don’t. - By the end of the book you will be able to use simple but powerful mathematical models to describe physiological circuits, turning details into useful understanding and new ways of thinking about treating diseases, including diabetes, autoimmune diseases, and age-related diseases such as lung fibrosis and cancer. The book explores (i) hormone circuits, (ii) immune...