This text is devoted to cellular evolution and to the biology of Cyanidium and other enigmatic cells. Twenty international experts present their views and reviews, postulating theories on compartmental (direct filiation) eukaryogenesis, discussing the endosymbiotic hypothesis and providing conceptions on molecular RNA and protein sequences of genes for phylogenetic applications.
This text is devoted to cellular evolution and to the biology of Cyanidium and other enigmatic cells. Twenty international experts present their views...
It all started with an observation. Edward Jenner, an English physician, observed that milkmaids who contracted cowpox were rarely victims of smallpox epidemic, a disease that in?icted a heavy toll on humankind with an estimate of 500 million victimsworldwide.In1796, Jennerinoculatedtheextracted?uidfromblistersonthe handofamilkmaidwhowasinfectedwithcowpoxintothearman8yearoldpeasant boy. After the boy recovered from a mild illness caused by this inoculation, Jenner exposed him to smallpox and to his delight the boy did not develop the disease. He published his work in 1798 in three...
It all started with an observation. Edward Jenner, an English physician, observed that milkmaids who contracted cowpox were rarely victims of smallpox...
Metastasis to bone is a common event in cancer. However, due to the skeleton's unique structure, exploring how cancer cells target the skeleton and interact with the bone microenvironment is challenging. The Biology of Skeletal Metastases covers areas that are important to both clinicians and basic scientists seeking an enhanced understanding of mechanisms of skeletal metastasis, as well as descriptions of cutting edge therapies for skeletal metastases.
Both increased efforts by many investigators and advances in research methodologies have provided a wealth...
Metastasis to bone is a common event in cancer. However, due to the skeleton's unique structure, exploring how cancer cells target the skeleton and...
Ovarian carcinoma continues to be responsible for more deaths than all other gynecologic malignancies combined, due to a continued inability to achieve detection of early (rather than advanced) stage disease and the lack of effective tumor-specific therapeutics.
Ovarian carcinogenesis, invasion, and metastatic dissemination require a complex cascade of interrelated genetic, molecular, and biochemical events that regulate the neoplastic transition of normal ovarian surface epithelium.
This updated second edition includes exciting new advances in ovarian cancer detection and...
Ovarian carcinoma continues to be responsible for more deaths than all other gynecologic malignancies combined, due to a continued inability to ach...
Pediatric and Adolescent Osteosarcoma provides a historical review of the nature of osteosarcoma and the conflict that accompanied the introduction of adjuvant therapy for osteosarcoma culminating in accepted and prevailing methods of current therapy. It outlines concepts in Epidemiology and Etiology, and provides chapters on pathology and radiologic characteristics of osteosarcoma, surgical therapy tailored specifically for treatment of primary tumors in pediatric/adolescent age group, treatment of pulmonary and extra pulmonary metastases and complications, as well as the role of...
Pediatric and Adolescent Osteosarcoma provides a historical review of the nature of osteosarcoma and the conflict that accompanied the introduction...
Endocrine Neoplasia is a comprehensive, updated, and clearly-written text covering the diseases for which endocrine surgical expertise is often needed. We look towards advances in the science and the art of endocrine surgery to continuously improve outcomes for our patients. The goal of this text was to provide a detailed description of both the underlying science of disease as well as the art of clinical management.
The book is divided into five sections addressing neoplasms of the thyroid, parathyroid, adrenal gland, neuroendocrine pancreas, and multiple endocrine neoplasia....
Endocrine Neoplasia is a comprehensive, updated, and clearly-written text covering the diseases for which endocrine surgical expertise is often nee...
Among the standard oncology modalities, surgical oncology is singular in that it lacks a separate board certification or even an added qualification mecha nism. 'Card-carrying' surgical oncologists are certified by the American Board of Surgery, as are all other general surgeons. What distinguishes the surgical oncologist is a set of cognitive skills rather than a specific armamentarium of surgical techniques. This different conceptual framework is derived from ex tensive additional training that leads to an in-depth understanding of the natural history and biologic behavior of the various...
Among the standard oncology modalities, surgical oncology is singular in that it lacks a separate board certification or even an added qualification m...
Policy and outcome studies represent a new area of research in oncology. Understanding the factors that affect quality of life, costs of care, patterns of care, and outcomes in oncology is important to providing comprehensive care. Health services is meant to be both a productive area of research as well as a discipline that improves patient decision making. In sum, Cancer Policy highlights some of the important areas of health services research in oncology.
Policy and outcome studies represent a new area of research in oncology. Understanding the factors that affect quality of life, costs of care, pattern...
There is no field of medicine in which advances in therapy have been so closely linked to a better understanding of molecular medicine than in the area of hematologic malignancies. For example, recent insights into the understanding of Epstein-Barr virus have led to new treatment options for patients with posttransplant lymphoproliferative disorders, as discussed in the chapter by Dr. Richard Ambinder et al. Similarly, Drs. Slack and Gallagher discuss the explosion of recent information regarding the molecular pathogenesis of acute promyelocytic leukemia. This particular morphologic subtype...
There is no field of medicine in which advances in therapy have been so closely linked to a better understanding of molecular medicine than in the are...
In recent years, there have been major advances in the treatment of patients with gynecologic malignancies. Perhaps the biggest advances have been in the area of ovarian cancer. Gynecologic Oncology focuses primarily upon this malignancy. This volume discusses cytoreductive surgery; screening for ovarian cancer; chemotherapy; new chemotherapeutic drugs; the controversy regarding the role of high-dose chemotherapy in gynecologic cancers; the hereditary basis for gynecologic malignancies; molecular genetics; molecular biology and new biologic therapies. Other topics covered...
In recent years, there have been major advances in the treatment of patients with gynecologic malignancies. Perhaps the biggest advances have been in ...
