I want to thank all who contributed to this first edition for their hard work and professionalism, and especially for their patience. I hope the readers will find this volume as helpful as I have found it. There is no doubt that the family of proteins we call the tubulins and the microtubules that they form when they aggregate are extremely important in the cell and, as we are increasingly learning, important in diseases that afflict so many. This field of investi- tion is a testament to how important both basic and clinical sciences are in understanding disease mechanisms and making inroads...
I want to thank all who contributed to this first edition for their hard work and professionalism, and especially for their patience. I hope the reade...
In Molecular Targeting in Oncology, authors present an overview of the development of targeted therapies for the treatment of cancer with an emphasis on clinical application. The volume covers the complexity of the rapidly developing area of targeted therapies for the treatment of patients with cancer and is structured in a way so readers may begin with chapters that most interest them and work through the rest of the chapters in the order of their choice.
The volume is divided into five sections that cover the most important elements of drug development. The first section focuses...
In Molecular Targeting in Oncology, authors present an overview of the development of targeted therapies for the treatment of cancer with an emphas...
Regional cancer therapies remain important options in the management of malignant disease, in spite of the venue of more targeted agents for systemic therapies. New te- nologies and better guidance systems for radiofrequency ablation and intrastitial laser therapies, highly selective intravascular approaches with improved catheters and gu- ance systems, improved agents for embolizations, and new vasoactive drugs for isolated limb and liver perfusions are just a few of the new developments in a field that is alive and progressing. Regional Cancer Therapy, so well put together by the editors...
Regional cancer therapies remain important options in the management of malignant disease, in spite of the venue of more targeted agents for systemic ...
Transforming Growth Factor-jl in Cancer Therapy, Volume I: Basicand Clinical Biology The present volume brings together a wealth of information that is fundamental to understanding the roleofTGF- in the pathogenesis, prevention, and treatment of cancer. It is not even 25 years sinceTGF- was first isolated and characterized as a dimeric pep tide from both human and bovine sources (1-3), but the entire fieldofTGF- research has grown and expanded so that it is now a central theme in all of cell biology. There is almost no tissue or organ in the mammalian body in whichTGF- does not playa central...
Transforming Growth Factor-jl in Cancer Therapy, Volume I: Basicand Clinical Biology The present volume brings together a wealth of information that i...
Transforming Growth Factor-B in Cancer Therapy, Volume II: Cancer Treatment and Therapy The chapters in this volume confer an abundance of knowledge about the current state ofour understanding oftransforming growth factor-B (TGF-B) in cancer treatment and therapy. Unlike several more traditional positive polypeptide growth factors that stim ulate cellular proliferation, the prototypical TGF-B is now known to inhibit the growth of most normal cell types, including those of epithelial and mesenchymal origin. However, there are examplesofcell types that can be stimulated by TGF-B under certain...
Transforming Growth Factor-B in Cancer Therapy, Volume II: Cancer Treatment and Therapy The chapters in this volume confer an abundance of knowledge a...
This book covers current topics related to the use of proteomic strategies in cancer therapy as well as anticipated challenges that may arise from its application in daily practice. It details current technologies used in proteomics, examines the use proteomics in cell signaling, presents clinical applications of proteomics in cancer therapy, and looks at the role of the FDA in regulating the use of proteomics.
This book covers current topics related to the use of proteomic strategies in cancer therapy as well as anticipated challenges that may arise from ...
In this volume, Supportive Care in Cancer Therapy, a part of the Cancer Drug Discovery and Development series, the contributors provide an up-to-date, concise review of specific consequences of cancer and its treatment. The book will assist those who care for the cancer patient to better understand all of the consequences of cancer and its treatment. In addition, the reader will gain thoughtful information on the care of the older patient as well as the dying patient.
In this volume, Supportive Care in Cancer Therapy, a part of the Cancer Drug Discovery and Development series, the contributors provide an up-to-da...
This book provides insight into established practices and research into apoptosis and senescence. The volume thoroughly examines novel and emerging techniques and research in the fields of cell death pathways, senescence growth arrest, drugs and resistance, DNA damage response, and other topics that still hold mysteries for researchers. In total, this volume provides basic scientists and clinicians with a deeper and more complete understanding of the cellular responses of malignancies which may determine the effectiveness of treatment, both in the initial stages of the disease as well as...
This book provides insight into established practices and research into apoptosis and senescence. The volume thoroughly examines novel and emerging...
Bioinformatics can be loosely defined as the collection, classification, storage, and analysis of biochemical and biological information using computers and mathematical algorithms. Although no single person or group started the field wholly on their own, Temple Smith, Ph.D., a professor at Boston University, is generally credited with coining the term. Bioinformatics represents a marriage of biology, medicine, computer science, physics, and mathematics, fields of study that have historically existed as mutually exclusive disciplines.
Concurrently,...
Bioinformatics can be loosely defined as the collection, classification, storage, and analysis of biochemical and biological information using comp...
