This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. elegans models of the tumor microenvironment are used to show how these models can lead to a greater understanding of the disease mechanisms that promote cancer progression.
This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. elegans models of the tumor microenvironment are...
In the vasculature, the extracellular matrix (ECM) is involved in the regulation of angiogenesis, vascular mechanosensing, and blood vessel stability.This book aims to provide the reader with an overview of the various roles of the ECM during angiogenesis and covers its important role for the maintenance of vascular integrity, capillary and arterial morphogenesis, as well as lymphangiogenesis. Furthermore, aspects of regulation of endothelial cell and pericyte functions by the ECM under physiological and pathological conditions are discussed. In addition, the reader will learn more about...
In the vasculature, the extracellular matrix (ECM) is involved in the regulation of angiogenesis, vascular mechanosensing, and blood vessel stability....
Integrins are heterodimeric cell surface receptors which anchor cells to different extracellular matrix proteins or act as cell-cell receptors. They play pivotal roles not only across a wide range of physiological processes including tissue morphogenesis, wound healing, and regulation of cell growth, but also in numerous pathological conditions such as autoimmunity, infectious disease, and carcinogenesis.This book aims to provide readers a summary of the most important integrins and their respective biological functions. Readers will learn about knockout- and animal models to study the...
Integrins are heterodimeric cell surface receptors which anchor cells to different extracellular matrix proteins or act as cell-cell receptors. They p...
