The book “Applied Assistive Technologies and Informatics for Students with Disabilities” provides a comprehensive guide to assist students with learning disabilities in higher education via modern assistive technologies and informatics. This book will take us on a tour of the various modern assistive technologies, such as artificial intelligence (AI), blockchain, computer vision (CV), text analytics (TA), the metaverse, human-computer interaction (HCI), digital twins (DT), and federated learning (FL), and how they support higher education students with learning disabilities.