Tuberculosis is a global health threat and the features of Mycobacterium tuberculosis and emergence of drug-resistant strains highlight the challenge it presents. This book shows how the challenge of tuberculosis is currently being met, providing insight into the evidence base underlying developments in diagnosis, drug development and treatment.

Resistance is on the rise among a variety of human pathogenic microorganisms associated with common and potentially life-threatening infections, including penicillin-resistant Streptococcus pneumonia and Methicillin-resistant Staphylococcus aureus (MRSA). There is increasing demand to approach the threat of multidrug resistance incorporating novel multidisciplinary methodologies and technological platforms. This book documents the latest research, covering current and promising activities in four key areas: computational chemistry and chemoinformatics, High Throughput Screening...