It is our pleasure to present this special volume on tissue engineering in the series Advances in Biochemical Engineering and Biotechnology. Thisvolume re?ects the emergence of tissue engineering as a core discipline of modern biomedical engineering, and recognizes the growing synergies between the technological developments in biotechnology and biomedicine. Along this vein, the focusof thisvolume istoprovide abiotechnology driven perspective on cell engineering fundamentals while highlighting their signi?cance in p- ducing functional tissues. Our aim is to present an overview of the state of...

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This book on the latest trends in modern biotechnology draws upon the relevant knowledge, methods and expertise from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science.

Cellulolytic Enzyme Production and Enzymatic Hydrolysis for Second-Generation Bioethanol Production, by Mingyu Wang, Zhonghai Li, Xu Fang, Lushan Wang und Yinbo QuBioethanol from Lignocellulosic Biomass, by Xin-Qing Zhao, Li-Han Zi, Feng-Wu Bai, Hai-Long Lin, Xiao-Ming Hao, Guo-Jun Yue und Nancy W. Y. Ho Biodiesel From Conventional Feedstocks, by Wei Du und De-Hua Liu Establishing Oleaginous Microalgae Research Models for Consolidated Bioprocessing of Solar Energy, by Dongmei Wang, Yandu Lu, He Huang und Jian XuBiobutanol, by Hongjun Dong, Wenwen Tao, Zongjie Dai, Liejian Yang, Fuyu Gong,...

Applications: - Applications of Microbial Cell Sensors, by Mifumi Shimomura-Shimizu and Isao Karube - Whole-Cell Bioreporters for the Detection of Bioavailable Metals, by Anu Hynninen and Marko Virta - Bacteriophage-Based Pathogen Detection, by Steven Ripp - Cell-Based Genotoxicity Testing, by Georg Reifferscheid and Sebastian Buchinger - Cytotoxicity and Genotoxicity Reporter Systems Based on the Use of Mammalian Cells, by Christa Baumstark-Khan, Christine E. Hellweg, and Gunther Reitz - Live Cell Optical Sensing for High Throughput Applications, by Ye Fang - Cyanobacterial Bioreporters as...

-Integration of Systems Biology with Bioprocess Engineering: L-Threonine Production by Systems Metabolic Engineering of Escherichia Coli, By Sang Yup Lee and Jin Hwan Park; -Analysis and Engineering of Metabolic Pathway Fluxes in Corynebacterium glutamicum, By Christoph Wittmann; -Systems Biology of Industrial Microorganisms, Marta Papini, Margarita Salazar, and Jens Nielsen; -De Novo Metabolic Engineering and the Promise of Synthetic DNA, By Daniel Klein-Marcuschamer, Vikramaditya G. Yadav, Adel Ghaderi, and Gregory N. Stephanopoulos; -Systems Biology of Recombinant Protein Production in...

DNA-chip analysis has come a long way since the first conference in Moscow in 1991. Nowadays, DNA-microarrays seem to be a common commodity in biological sciences. The complexity hidden behind the apparent ease of such studies, however, is highlighted by the fact that it took about ten years before the methodology really set off. Also, on closer scrutiny, one realises that some problems still remain. Nevertheless, microarrays produce data on a scale beyond imagination a few years ago. The authors of the book took part in bringing this about. They are well-known experts in the field, many -...

The immobilized biocatalyst (IMB) is a key component of biotransformation systems that are used to transform substrates to desired products. The impro- ment of biocatalyst properties has a direct influence on the overall effectiveness of the process based on the biotransformation. The basic catalytic characte- stics of biocatalyst that are followed include kinetic properties, pH optima, stability,and inhibition. The investigation of catalytic properties of immobilized enzymes is still a time consuming procedure and is not always simple. In the 1980s,a major effort was made to standardize the...

In this special issue review articles summarize the most outstanding features of microorganisms that can survive under extreme conditions. These microorganisms are adapted to living at 100 C in volcanic springs, at low temperatures in the cold polar seas, at high pressure in the deep sea, at very low and high pH values (pH 0-1 or pH 10-11), or at very high salt concentrations (35%). The latest findings on the molecular biology and the protein structure of these exotic organisms are presented. In addition, the potential applications of extremophiles are reviewed, including the production of...