R. B. Stein Department of Physiology, University of Alberta, Edmonton, Canada The impetus for this volume and the conference that gave rise to it was the feeling that studies on motor control had reached a turning point. In recent years, studies on motor units and muscle receptors have become increasingly detailed. Attempts to integrate these studies into quantitative models for the spinal control of posture have appeared and preliminary attempts have been made to include the most direct supraspinal pathways into these models (see for example the chapters by Nashner and Melvill Jones et al....

This volume, the sixth in the IBAGS series, summarizes major contributions in clinical and basic research on the basal ganglia. The sixth meeting of the Society was held on Cape Cod, in the state of Massachusetts, USA, in October, 1998. Altogether 16 countries were represented by 227 participants. This volume contains papers contributed by participants. The focus of the sixth triennial IBAGS meeting, and of this volume, was to bring to- gether leaders in basic and clinical science to address two sets of still-persisting questions in the field. The first set focuses on the functions of the...

This volume, The Basal Ganglia VII, is derived from the proceedings ofthe Seventh Triennial Meeting of the International Basal Ganglia Society (IBAGS). The Meeting was held from II - 15 February 2001 at The Copthorne Resort, Waitangi, Bay of Islands, New Zealand, the site of the signing of the Treaty ofWaitangi in 1840 and the traditional birth-place of the New Zealand Nation. As at previous Meetings, our aim was to hear and discuss new ideas and research developments on the basal ganglia and the implications of these findings for novel treatment strategies for basal ganglia disorders. The...

Alzheimer's disease is one the foremost health problems facing every society fortunate enough to attain a level of medical care that ensures an average lifespan of over 70 years of age. The cause of the disease remains unknown, and no single therapeutic approach has yet been found highly efficacious. Indeed, as the complexity of its effects on brain neuronal systems becomes elucidated, the concept emerges that Alzheimer's disease may be an umbrella term for multiple Alzheimer's-type syndromes that can be differentiated based on etiology (hereditary versus sporadic), neurochemical deficits,...

''Emphasis on new issues and emerging concepts insures that the information presented is still timely...A compelling source of information on recent research in the field.'' ---Journal of Chemical Neuroanatomy, May 1997

This book is devoted to the description of agenesis of the corpus callosum, a congenital malformation of midline structures in the brain that may be regarded as a natural model of the "split-brain. " First reported by Rei in 1812, this anomaly has since been described by several investigators. Interest in this malformation was revived in the 1970s by studies of interhemispheric transfer in Bogen and Vogel's commissurotomized patients and the subsequent findings by Sperry that acallosal patients were devoid of the typical disconnection deficits found in patients with surgical transection of...

The neuronal cytoskeleton is a complex structure responsive to both intrinsic and extrinsic factors. Defined populations of neurons in the brains of patients with Alzheimer and several other neurodegenerative diseases contain abnormal filamentous accumulations which share elements with the cytoskeleton. Although there is a general consensus that these abnormal filaments do contain cytoskeletal elements, much debate remains regarding which cytoskeletal elements are incorporated and whether the cytoskeletal rearrangement is primary or secondary to other cellular changes. In this book these...

Nicotine is the major factor in the continuation of the smoking habit among humans. On December 2-4, 1985, under the sponsorship of the Tobacco and Health Research Institute in Lexington, Kentucky, leading scientists from around the world whose research efforts have focused on the role of nicotine in the tobacco habit participated in an International Symposium to provide the most comprehensive and xtensive coverage of this topic so far. The material discussed was in the forefront of man's knowledge about nicotine, and both lectures and question and answer sessions were stimulating and...

The i nterna ti ona 1 symposi a on transcutaneous monitori ng have dea It with the interaction between ideas and research, the introduction of unconventional techniques into clinical practice, and the joint efforts of researchers, clinicians, and industry to design and manufacture prac tical equipment for noninvasive monitoring. The First International Symposium on Continuous Transcutaneous Blood Gas Monitoring took place in Marburg, West Germany, from May 31 to June 2, 1978. This was the first major international meeting exclusively devoted to transcutaneous blood gas monitoring, and it was...

This book is the outcome of an international conference, held at the Aviya Sonesta Hotel in Eilat, Israel, on March 24-27, 1985. This was the 30th in a series of the annual OHOLO Conferences, sponsored by the Israel Institute for Biological Research. Participants in this Conference consisted of scientists from four teen countries; represented a broad spectrum of research interests; and included a well-balanced representation from academia, clinical institutions and pharmaceutical industry. The book includes talks, poster sessions, and a comprehensive general discussion, all from the...