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This focused monograph builds upon an increasing interest in nonholonomic mechanical systems in robotics and control engineering. It covers the definition and development of new nonholonomic machines designed on the basis of nonlinear control theory for nonholonomic mechanical systems.

Results presented in this book showed that mutating Ile41 and Ala42 to hydrophilic residues increases solubility, while mutating the same residues to hydrophobic residues enhances the aggregation propensity. This result suggests that the enhanced aggregation propensity of Abeta42 relative to Abeta40 results from the hydrophobic nature of Ile41 and Ala42 residues (Chapter 2). Fusions of GFP to Abeta mutants containing 8 12 mutations of hydrophobic residues to other hydrophobic residues produced white phenotypes, suggesting that generic hydrophobicity (rather than specific nonpolar side chains)...

This book analyzes the three questions in political competition: Who wins? What position does a candidate take? Why are some candidates policy- oriented but others are valence-oriented? Chapter 2 attempts to answer these questions by presenting a formal model that brings the spatial theory of voting and empirical studies together. The model specifies electoral competition as revolving around candidates positions and valences. Two candidates spend their resources on valences to sway citizens voting decisions but they are constrained by their party activists providing them with electoral...