a. Physical base of the Intrinsic Optical Imaging (IOS)
b. Technical principles of the functional brain mapping based on IOS and their practical realization in a following imaging system: direct IOS, transcranial IOS (near-infrared spectroscopy – NIRS), optical coherence tomography (OCT), Photoacoustic Tomography (PA).
3. Extrinsic Optical Imaging 3.1 Chemical base of the extrinsic optical imaging 3.2 Description of main functional-sensitive fluorescence indicators: voltage-sensitive dye, calcium-sensitive dye, Ph-sensitive dye, Cl-sensitive dye 3.3 Genetically encoded voltage- and calcium sensitive indicator
3.4 Technical realization of the extrinsic optical imaging: 1- and 2-photon imaging
4 Main achievements of the brain optical imaging in neuroscience and perspectives of its further development for various applications in clinical and biomedical studies.
5 Summary and Conclusions
Professor Igor Meglinski, MSc, PhD, is a Head of Opto-Electronics and Measurement Techniques Laboratory in the University of Oulu (Finland). For the last 20 years, his research interests lie at the interface between physics, optical and biomedical engineering, sensor technologies and life sciences, focusing on the development of new non-invasive imaging/diagnostic techniques and their application in medicine & biology, material sciences, pharmacy, food, environmental monitoring, and health care industries. He is the Node Leader in Biophotonics4Life Worldwide Consortium (BP4L), Fellow of the Institute of Physics (UK), and Fellow of SPIE. Professor Meglinski is the author and co-author of over 220 papers in peer-reviewed scientific journals, proceedings of international conferences, books, book chapters, patents and professional magazines; over 450 presentations at major international conferences, symposia and workshops, including over 200 invited lectures and plenary talks. Professor Meglinski is highly regarded for his research in Biophotonics and sensor technologies and their wide range of uses in practical applications.