Gnotobiotics

ISBN-13: 9780128045619 / Angielski / Twarda / 2017 / 428 str.

Trenton R. Schoeb; Kathryn A. Eaton

Opis

Gnotobiotics summarizes and analyzes the research conducted on the use of gnotobiotes, providing detailed information regarding actual facility operation and derivation of gnotobiotic animals. In response to the development of new tools for microbiota and microbiome analysis, the increasing recognition of the various roles of microbiota in health and disease, and the consequent expanding demand for gnotobiotic animals for microbiota/microbiome related research, this volume collates the research of this expanding field into one definitive resource.

• Reviews and defines gnotobiotic animal species
• Analyzes microbiota in numerous contexts
• Presents detailed coverage of the protocols and operation of a gnotobiotic facility

Spis treści

1. Historical Overview 2. Principles of Establishing and Operating a Gnotobiotic Facility 3. Procedures for Rodents 4. Developing a Business Plan for a Gnotobiotics Program 5. Gnotobiotic Pigs: From Establishing a Facility to Modeling Human Infectious Diseases 6. Gnotobiotic Fish as Models to Study Host-Microbe Interactions 7. Use of Gnotobiotic Mice in the Study of Metabolic Syndrome 8. Gnotobiotics and Inflammatory Bowel Disease