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This book offers an in-depth discussion of the latest strategies in the field of drug design and their applications in various disorders, in order to encourage readers to undertake their own projects.It also includes the contemporary application of drug-designing methodologies to inspire others to further expand the utility of this field in other diseases.It is intended for advanced undergraduate and graduate students, postdocs, researchers, lecturers and professors in bioinformatics, computational biology, medicine, pharmaceutics and other related fields.

This edited volume while focusing on participatory governance in the Great Lakes basin of North America also gives a comparative perspective of the African Great Lakes. The book describes the actions taken at degraded locations along the Great Lakes in North America through Remedial Action Plans (RAP) and other mechanisms, with an aim to highlight the successes and failures encountered in ecosystembased regenerative approaches. The book documents these experiences including the lead taken by industry in improving environmental quality of the Great Lakes. The book concludes with lessons...

This book presents the views of various international law and human rights experts on the contested meaning, scope of application, value and viability of R2P; the principle of the Responsibility to Protect . R2P refers to the notion that the international community has a legal responsibility to protect civilians against the potential or ongoing occurrence of the mass atrocity crimes of genocide, large scale war crimes, ethnic cleansing and crimes against humanity. R2P allows for intervention where the individual State is unable or unwilling to so protect its people or is in fact a...

Want to create animated graphics for iPhone, iPad, and the Web, using familiar Adobe features? You ve come to the right guide. Adobe Edge Animate Preview 7: The Missing Manual shows you how to build HTML5 graphics with Adobe visual tools. No programming experience? No problem. Adobe Edge Animate writes all the code for you. With this book, you ll be designing great-looking web elements in no time.

The important stuff you need to know:

• Get to know the workspace. Learn how Adobe Edge Animate performs its magic.
• Create and import graphics. Make...

Dad's words come as a complete shock to Essie. How can he just walk out on her and the family, especially when Mom is pregnant?

Essie keeps her dad's leaving a secret. Then Essie's classmate, Chris Crow, disappears, and everyone finds out he's been kidnapped. Is Chris okay? Is Dad ever coming back? Essie is left to wonder if people really have any control over what happens in their lives.

Finally, after a startling incident with a family friend, Essie finds the strength to hold on tight to all that she has left -- and in the process realizes that the bonds of...