Pharmaceutical Nanotechnology: Basic Protocols

ISBN-13: 9781493995189 / Angielski / Miękka / 2020 / 398 str.

Volkmar Weissig;Tamer Elbayoumi

Opis

This volume details protocols on formulation, surface modification, characterization, and application of a variety of pharmaceutical nanocarriers such as micelles, nanoparticles, dendrimers, carbon dots, polymersomes, and others. Chapters are targeted toward investigators working in academic and industrial laboratories conducting research in the broad field of pharmaceutical sciences, with an emphasis on drug delivery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Pharmaceutical Nanotechnology: Basic Protocols aims to be a source of inspiration to all investigators who are interested in the potential of the merger of nanotechnology with pharmaceutical sciences.

Spis treści

1. Nanovesicles for Nanomedicine: Theory and Practices

            Sheetu Wadhwa, Varun Garg, Monica Gulati, Bhupinder Kapoor, Sachin Kumar Singh, and Neeraj Mittal

 

2. Preparation and Characterization of Micelles

            Vandana B. Patravale, Prashant G. Upadhaya, and Ratnesh D. Jain

 

3. Anionic and Cationic Vitamin E-TPGS Mixed Polymeric Phospholipid Micellar Vehicles

            Mingyi Yao and Tamer Elbayoumi

 

4. Phospholipid Micelles for Peptide Drug Delivery

            Karina Esparza, Dulari Jayawardena, and Hayat Onyuksel

 

5. Design, Preparation, and Characterization of Peptide-Based Nanocarrier for Gene Delivery

            Mohsen Alipour and Saman Hosseinkhani

 

6. Gelatin Nanoparticles

            Rania M. Hathout and Abdelkader A. Metwally

 

7. Green Synthesis of Chitosan-Silver/Gold Hybrid Nanoparticles for Biomedical Applications

            Ibrahim M. El-Sherbiny and Mohammed Sedki

 

8. Methods of Fabrication of Chitosan-Based Nano-in-Microparticles (NMPs)

            Ibrahim M. El-Sherbiny and Amr Hefnawy

 

9. Fabrication of Mucoadhesive-Dendrimers as Solid Dosage Forms

            Nidhi Raval, Rahul Maheshwari, Kiran Kalia, and Rakesh Kumar Tekade

 

10. In Situ Vaccination of Tumors Using Plant Viral Nanoparticles

            Abner A. Murray, Mee Rie Sheen, Frank A. Veliz, Steven N. Fiering, and Nicole F. Steinmetz

 

11. Bioconjugation in Drug Delivery: Practical Perspectives and Future Perceptions

            Perihan Elzahhar, Ahmed S.F. Belal, Fatema Elamrawy, Nada A. Helal, and Mohamed Ismail Nounou

 

12. Conjugation of Triphenylphosphonium Cation to Hydrophobic Moieties to Prepare Mitochondria-Targeting Nanocarriers

            Diana Guzman-Villanueva, Mark R. Mendiola, Huy X. Nguyen, Francis Yambao, Nusem Yu, and Volkmar Weissig

 

13. Surface Modification of Biomedically Essential Nanoparticles Employing Polymer Coating

            Rahul Maheshwari, Nidhi Raval, and Rakesh Kumar Tekade

 

14. Peptide-Modified Gemini Surfactants: Preparation and Characterization for Gene Delivery

            Mays Al-Dulaymi, Waleed Mohammed-Saeid, Anas El-Aneed, and Ildiko Badea

 

15. Preparation of Responsive Carbon Dots for Anticancer Drug Delivery

            Tao Feng and Yanli Zhao

 

16. Surface Modification of Nanoparticles and Nanovesicles via Click Chemistry

            Matthias Voigt, Thomas Fritz, Matthias Worm, Holger Frey, and Mark Helm

 

17. Polymersomes: Preparation and Characterization

            Yumiao Hu and Liyan Qiu

 

18. Partially Polymerized Phospholipid Vesicles for Efficient Delivery of Macromolecules

            Megha Goshi, Nicholas Pytel, and Tamer Elbayoumi

 

19. Fabrication of Nanostructured Lipid Carriers (NLC)-Based Gels from Microemulsion Template for Delivery through Skin

            Medha D. Joshi, Rashmi H. Prabhu, and Vandana B. Patravale

 

20. Preparation and Characterization of Solid Lipid Nanoparticles-Based Gel for Topical Delivery

            Vandana B. Patravale and Amit G. Mirani

 

21. Molecular-Level “Observations” of the Behavior of Gold Nanoparticles in Aqueous Solution and Interacting with a Lipid Bilayer Membrane

            Priyanka A. Oroskar, Cynthia J. Jameson, and Sohail Murad

 

22. Atomic Force Microscopy for Cell Membrane Investigation

            Mingjun Cai and Hongda Wang

 

23. Physico-Chemical Characterization of Phthalocyanine-Functionalized Quantum Dots by Capillary Electrophoresis Coupled to a LED Fluorescence Detector

            Gonzalo Ramírez-García, Fanny d’Orlyé, Tebello Nyokong, Fethi Bedoui, and Anne Varenne

 

24. In Vitro Testing of Anticancer Nanotherapeutics Using Tumor Spheroids

            Avanti Ganpule, Zishu Gui, Mohammed A. Almuteri, and Gerard G.M. D’Souza