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This Open access book provides an overview of the cutting-edge research to systematize innovative foundations in algorithmic theories and techniques, and apply them to solve socially significant real-life problems, thereby driving social transformation and advancement. Formulating such social problems into well-defined mathematical or computational terms requires not only a solid theoretical foundation but also a deep understanding of the application domain itself. The content is divided into three parts. Following an introductory chapter in Part I, Part II discusses how to bridge the gap...

This book presents a comprehensive, innovative, integrated, and empirically effective system for cross-sectionally analyzing prices of government bonds (GBs) and corporate bonds (CBs) to timely obtain practically useful information on yield curves and default curves. The system consists of (1) GB-pricing model that values coupon GB and gives yield curve, (2) credit risk rating model of each CB, and (3) CB-pricing model that gives default curve or equivalently term structure of default probabilities (TSDP), which prices credit default swap (CDS). And in view of data science, the empirical...

This text aims to provide practical models and methods for the quantitative analysis of financial asset prices, construction of various portfolios, and computer-assisted trading systems. In particular, it should be helpful reading for Quants (quantitatively-inclined analysts) in financial industries, financial engineers in investment banks; securities companies, derivative-trading companies, and software houses who are developing portfolio trading systems; graduate students and specialists in the areas of finance, business, hardbound economics, statistics, financial engineering; investors who...

This volume is a practical guide of theranostics using intraoperative fluorescence imaging technology, as an all-out effort by the Japanese Society for Fluorescence Guided Surgery. It describes the various approaches the technique is being used such as vascular imaging, identification of lymphatic vessels by intratissue injection, lymph node imaging, and imaging for identification of anatomical structures. The book is organized into three major parts and the first one delivers the basics, introducing the use of the technology in clinical settings and initial setups. Next comes the description...

Methamphetamine is one of the most widely abused stimulants and together with amphetamine has led to serious social problems. Numerous papers in the fields of medicine, toxicology, pharmacology, sociology, etc. have appeared. In Japan for example about 20,000 to 22,000 persons have been arrested in recent years on suspicion of abuse, smuggling or illegal manufacture of drugs. In other countries, stimulant drugs also present social problems and efforts have been directed toward prevention. Although marked development of analytical techniques in the field of forensic sciences has been achieved,...