Ocular dispersions for dry eye syndrome management

ISBN-13: 9786206754527 / Angielski / Miękka / 216 str.

Tamilvanan Shunmugaperumal; Syed Nazrin Ruhina Rahman

Opis

Highlighting the use of colloidal dispersions as eyedrop formulations containing single or dual drugs has garnered significant interest. This book covers the development of formulas, preclinical safety evaluation, and animal studies for single drug-loaded emulsion eyedrops. It explains how to convert liquid-retentive eyedrops into solid-dry powder for reconstitution, prolonging colloidal stability. Applying a polymer coat to dispersed oil droplets forms nanocapsules, extending drug release in nanocapsule-based eyedrops. The book elucidates two-compartment formation in nanocapsules and emulsion eyedrops, accommodating different drugs without interactions. Dual drug-loaded colloidal dispersions manage moderate to severe dry eye syndrome, achieving combination therapy and inflammation reduction.

O autorze

Prof. (Dr.) Tamilvanan and Mrs. Syed Nazrin Ruhina Rahman are working on the development of single or dual drug-loaded colloidal dispersion eyedrops for managing dry eye syndrome. They have also created a bi-compartmental structure within the dispersed phase of colloidal dispersion eyedrops to entrap two different drugs.