Biology of Mycobacterial Lipids

ISBN-13: 9780323919487 / Angielski / Miękka / 2022

Zeeshan Fatima; Stephane Canaan

Spis treści

1. An overview of mycolic acids: structure-function-classification, biosynthesis, and beyond 2. Lipid biosynthetic pathways as potential drug targets for emerging mycobacterial pathogens 3. Mycobacterial lipids in the host-pathogen interface: roles in pathogenesis and host immune response 4. Lipids and glycolipids as biomarkers of mycobacterial infections 5. Multifaceted roles of mycobacterium cell envelope glycolipids during host cell membrane interactions 6. Conserved mechanisms drive host-lipid access, import, and utilization in Mycobacterium tuberculosis and M. marinum 7. Biological implications of mycobacterial lipids on NKT-cells stimulation 8. The effect of chemically synthetic mycobacterial mycolates on phospholipidome immunomodulation of murine macrophages 9. Polyketide synthases in mycobacterial lipid metabolism 10. Understanding mycobacterial lipid metabolism and employing it as a tool to produce attenuated TB vaccine candidates 11. Deciphering the physiological role of serine enzymes involved in mycobacterial lipid metabolism using activity-based protein profiling 12. Intrabacterial lipid inclusions: overview of an amazing organelle 13. Multiple facets and functions of the toxin mycolactone produced by Mycobacterium ulcerans