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Quality, safety and effectiveness must be built into the product. This requires careful attention to a number of factors such as the selection of quality materials/components, product and process design, control of processes, in-process control, and end-product testing. Due to the complexity of the drug products, routine end-product testing alone is not sufficient due to several reasons. Furthermore, quality cannot be tested into the finished drug product but rather be built in the manufacturing processes and these processes should be controlled in order that the finished product meets all...

While orthodontic treatment affects all three dimensions, many of the current tools of diagnosis employ only a two dimensional (2D) representation of the patient. The development of integrated 3-D tools has helped to interpolate the 3-D data and visualize a 3-dimensional problem 3-dimensionally and treat accordingly. Highly sophisticated technologies from the fields of digital imaging, computer graphics, robotics, computational analysis and database management are cruising their way into the specialty. With treatment records always at the orthodontist's finger tips, orthodontic treatment has...