Wyniki wyszukiwania:

By consistently dedicating efforts to multi-omic and other high-throughput technologies, it is expected that RNA therapies will have a vital role in future personalized medicine approaches for cancer therapy. Within this framework, analyzing the genetic sequence of a patient's tumor would allow for the detection of crucial driver mutations or changes that cause resistance to drugs. These mutations may then be targeted with RNA therapies that are particularly designed to treat those particular variations. Recent clinical trials have shown that RNA-based therapies hold great potential for...

Ovarian follicles are the basic structural and functional unit of the mammalian ovary. Follicles contain an oocyte or female gamete, its surrounding granulosa cells, a basement membrane, and associated thecal cells. Development of the ovarian follicles from a small preantral follicle to the large pre-ovulatory follicle is key process in mammalian reproduction. From birth, ovary of the female contains a large number of immature, primordial/prenatral follicles. However, most of the follicles undergoes atresia and only few number of follicles reached to the ovulatory stage. The present knowledge...