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Pediatric T.B. is very much prevalent in modern India. Isoniazid, a most commonly used drug, is available in form of tablet and liquid orals but till today no extended release liquid oral is available for pediatric patients. Hence, an attempt is made to formulate multiple emulsion system of Isoniazid. In this study multiple emulsion batches were formulated by double emulsification method with Isopropyl myristate, Span-83 and Tween-80 with Polyvinylpyrolidone (P.V.P.) as a stabilizer. All batches were characterized for average globule size, rheological evaluation, % drug entrapment and...

One of the most feasible approaches for achieving a prolonged and predictable drug delivery profile in the GI tract is to control the gastric residence time (GRT) via gastroretentive drug delivery system which will provide us with new and important therapeutic options. Controlling the residence time of a drug delivery system in a particular region of GI tract can utilize several approaches which include floating drug delivery system, high density system and mucoadhesive system. Helicobacter pylori bacteria are the causative agents of gastric ulcers.Certain conventional dosage forms fail to...