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This work uses advances in Real Options
Theory to develop a theoretical model of the migration
decision under uncertainty. Prospective migrants face a
future that evolves in new and unexpected ways, and the
flexibility in responding to new conditions is an important
consideration in the original decision to migrate. Real
Options theory allows us to value this strategic
flexibility as the future unfolds. Two specific instances
of migration are analyzed within this framework: a
...

Generation of foam cells, an essential step for reverse cholesterol transport (RCT) studies, uses the technique of receptor dependent macrophage loading with radiolabeled acetylated Low Density Lipoprotein (Ac-LDL). In this study, we used the ability of a biologically relevant detergent molecule, Lysophosphatidylcholine (Lyso PtdCho), to form mixed micelles with cholesterol or cholesteryl ester (CE) to generate macrophage foam cells. Fluorescent or radiolabelled cholesterol / Lyso PtdCho mixed micelles were prepared and incubated with RAW 264.7 or mouse peritoneal macrophages. Results showed...